HitPredict

Interactor 1: MYC (P01106)
Myc proto-oncogene protein (Class E basic helix-loop-helix protein 39) (bHLHe39) (Proto-oncogene c-Myc) (Transcription factor p64)
Gene: MYC

Interactor 2: MK01 (P28482)
Mitogen-activated protein kinase 1 (MAP kinase 1) (MAPK 1) (EC 2.7.11.24) (ERT1) (Extracellular signal-regulated kinase 2) (ERK-2) (MAP kinase isoform p42) (p42-MAPK) (Mitogen-activated protein kinase 2) (MAP kinase 2) (MAPK 2)
Gene: MAPK1

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.82 0.60 0.705

The method score is based on:

Property Details
Experiments 15210690, 29467282, 7957875, 31638140
Identification Methods pull down, affinity chromatography technology, protein kinase assay
Interaction Type direct interaction, physical association, phosphorylation reaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0003677 - DNA binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
GO:0006974 - DNA damage response
and 2 others

more...
Homologous interactions 7

Homologous interactions

Color coding for hit scores

1 454
Hs

1 360
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ At

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024