HitPredict

Interactor 1: MYC (P01106)
Myc proto-oncogene protein (Class E basic helix-loop-helix protein 39) (bHLHe39) (Proto-oncogene c-Myc) (Transcription factor p64)
Gene: MYC

Interactor 2: HSP74 (P34932)
Heat shock 70 kDa protein 4 (HSP70RY) (Heat shock 70-related protein APG-2) (Heat shock protein family H member 2)
Gene: HSPA4

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.68	0.60	0.640

Property	Details
Experiments	29467282, 35013218, 36424410
Identification Methods	affinity chromatography technology, proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 454 Hs			1 840
+	Hs
		320784 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		HS74L_HUMAN (1-840): 0: 959: 63.21
+	Hs
		347469 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		HS105_HUMAN (1-840): 0: 938: 62.95
+	Hs
		379064 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		HSP74_HUMAN (1-840): 0: 993: 100.00
+	Hs
		320788 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		HS74L_HUMAN (1-840): 0: 959: 63.21
+	Hs
		379670 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		HS105_HUMAN (1-840): 0: 938: 62.95
+	Hs
		320861 USF2_HUMAN (180-454): 1.78e-35: 136: 15.99		HS74L_HUMAN (1-840): 0: 959: 63.21
+	Hs
		345782 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		HSP7C_HUMAN (564-692): 5.97e-20: 97: 16.92
+	Hs
		346070 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		HS71L_HUMAN (564-691): 7.22e-19: 93.5: 22.48
+	Hs
		345856 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		HSP76_HUMAN (587-690): 1.94e-16: 85.8: 22.86
+	Hs
		378955 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		HSP7C_HUMAN (564-692): 5.97e-20: 97: 16.92