HitPredict

Interactor 1: MYC (P01106)
Myc proto-oncogene protein (Class E basic helix-loop-helix protein 39) (bHLHe39) (Proto-oncogene c-Myc) (Transcription factor p64)
Gene: MYC

Interactor 2: K22E (P35908)
Keratin, type II cytoskeletal 2 epidermal (Cytokeratin-2e) (CK-2e) (Epithelial keratin-2e) (Keratin-2 epidermis) (Keratin-2e) (K2e) (Type-II keratin Kb2)
Gene: KRT2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	29467282, 35013218
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 454 Hs			1 639
+	Hs
		345690 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		K2C8_HUMAN (150-535): 1.29e-143: 427: 59.33
+	Hs
		345661 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		K2C1_HUMAN (143-509): 1.63e-112: 353: 71.94
+	Hs
		347231 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		K2C73_HUMAN (1-598): 8.9e-92: 296: 51.00
+	Hs
		345816 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		K2C5_HUMAN (1-494): 7.49e-82: 271: 61.48
+	Hs
		345660 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		K2C6B_HUMAN (5-510): 8.35e-82: 270: 61.22
+	Hs
		347191 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		K2C1B_HUMAN (58-509): 2.24e-79: 264: 61.95
+	Hs
		345637 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		K2C6A_HUMAN (5-510): 8.33e-78: 259: 61.22
+	Hs
		378892 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		K2C1_HUMAN (143-509): 1.63e-112: 353: 71.94
+	Hs
		378970 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		K2C5_HUMAN (1-494): 7.49e-82: 271: 61.48
+	Hs
		379559 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		K2C1B_HUMAN (58-509): 2.24e-79: 264: 61.95
+	Hs
		359449 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		K2C6A_HUMAN (5-510): 8.33e-78: 259: 61.22
+	Hs
		379075 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		K22E_HUMAN (1-517): 4.22e-68: 235: 100.00