HitPredict

Interactor 1: MYC (P01106)
Myc proto-oncogene protein (Class E basic helix-loop-helix protein 39) (bHLHe39) (Proto-oncogene c-Myc) (Transcription factor p64)
Gene: MYC

Interactor 2: LIS1 (P43034)
Platelet-activating factor acetylhydrolase IB subunit beta (Lissencephaly-1 protein) (LIS-1) (PAF acetylhydrolase 45 kDa subunit) (PAF-AH 45 kDa subunit) (PAF-AH alpha) (PAFAH alpha)
Gene: PAFAH1B1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	29467282
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 454 Hs			1 410
+	Hs
		346404 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		WDR5_HUMAN (4-323): 1.79e-70: 226: 25.38
+	Hs
		346449 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		GBB2_HUMAN (166-410): 8.15e-51: 175: 20.48
+	Hs
		348035 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		NLE1_HUMAN (1-219): 4.29e-44: 161: 22.51
+	Mm
		348444 MYC_MOUSE (1-454): 4.33e-119: 357: 89.01		FBXW7_MOUSE (1-257): 1.21e-45: 169: 19.70
+	Hs
		209372 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		PLRG1_HUMAN (224-409): 3.04e-43: 159: 24.73
+	Hs
		347517 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		FBXW7_HUMAN (261-409): 5.02e-27: 115: 30.00
+	Hs
		347550 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		SNR40_HUMAN (328-408): 1.73e-17: 85.2: 26.83
+	Hs
		346472 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		RACK1_HUMAN (103-261): 2.66e-16: 80.9: 33.13
+	Hs
		196936 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		PRP4_HUMAN (324-409): 2.67e-13: 73.3: 15.96
+	Hs
		379200 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		WDR5_HUMAN (4-323): 1.79e-70: 226: 25.38
+	Dm
		1375911 MYC_DROME (210-454): 3.25e-30: 126: 26.74		FBXW7_DROME (50-403): 2.3e-74: 254: 27.52
+	Hs
		607803 USF1_HUMAN (175-453): 1.02e-39: 146: 18.40		WDR5_HUMAN (4-323): 1.79e-70: 226: 25.38
+	Hs
		209375 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		PLRG1_HUMAN (224-409): 3.04e-43: 159: 24.73
+	Hs
		903353 MGAP_HUMAN (151-449): 1.22e-27: 118: 17.71		WDR5_HUMAN (4-323): 1.79e-70: 226: 25.38
+	Mm
		1112323 SRBP2_MOUSE (124-446): 2.23e-37: 147: 13.60		FBXW7_MOUSE (1-257): 1.21e-45: 169: 19.70
+	Hs
		379688 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		FBXW7_HUMAN (261-409): 5.02e-27: 115: 30.00
+	Mm
		1257396 SRBP1_MOUSE (172-453): 4.45e-35: 140: 16.61		FBXW7_MOUSE (1-257): 1.21e-45: 169: 19.70
+	Hs
		379701 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		SNR40_HUMAN (328-408): 1.73e-17: 85.2: 26.83
+	Hs
		379258 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		RACK1_HUMAN (103-261): 2.66e-16: 80.9: 33.13
+	Hs
		738987 SRBP1_HUMAN (95-453): 2.54e-33: 135: 16.19		FBXW7_HUMAN (261-409): 5.02e-27: 115: 30.00