HitPredict

Interactor 1: MYC (P01106)
Myc proto-oncogene protein (Class E basic helix-loop-helix protein 39) (bHLHe39) (Proto-oncogene c-Myc) (Transcription factor p64)
Gene: MYC

Interactor 2: MAGA4 (P43358)
Melanoma-associated antigen 4 (Cancer/testis antigen 1.4) (CT1.4) (MAGE-4 antigen) (MAGE-41 antigen) (MAGE-X2 antigen)
Gene: MAGEA4

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	29467282, 36424410
Identification Methods	affinity chromatography technology, proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0005634 - nucleus GO:0043066 - negative regulation of apoptotic process
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 454 Hs			1 317
+	Hs
		346164 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		MAGA1_HUMAN (1-304): 5.04e-137: 392: 74.34
+	Hs
		347613 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		MAGBA_HUMAN (1-312): 3.98e-129: 373: 40.64
+	Hs
		180191 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		MAGB2_HUMAN (1-315): 5.52e-114: 334: 41.88
+	Hs
		348234 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		MAGD2_HUMAN (13-310): 2.81e-104: 318: 30.10
+	Hs
		348372 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		MAGD1_HUMAN (23-307): 1.76e-90: 287: 29.93
+	Hs
		347691 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		NECD_HUMAN (17-313): 6.32e-94: 283: 27.04
+	Hs
		796341 MAD3_HUMAN (320-450): 1.2e-25: 105: 26.72		MAGAB_HUMAN (1-317): 3.14e-152: 435: 62.19
+	Hs
		180192 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		MAGB2_HUMAN (1-315): 5.52e-114: 334: 41.88