HitPredict

Interactor 1: MYC (P01106)
Myc proto-oncogene protein (Class E basic helix-loop-helix protein 39) (bHLHe39) (Proto-oncogene c-Myc) (Transcription factor p64)
Gene: MYC

Interactor 2: KI67 (P46013)
Proliferation marker protein Ki-67 (Antigen identified by monoclonal antibody Ki-67) (Antigen KI-67) (Antigen Ki67)
Gene: MKI67

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	29467282, 36424410
Identification Methods	affinity chromatography technology, proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003677 - DNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005730 - nucleolus
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 454 Hs			1 3256
+	Hs
		379107 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		KI67_HUMAN (1-3256): 0: 1046: 100.00
+	Hs
		801237 MGAP_HUMAN (151-449): 1.22e-27: 118: 17.71		KI67_HUMAN (1-3256): 0: 1046: 100.00
+	Hs
		346499 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		MAP1A_HUMAN (139-2564): 8.72e-104: 377: 10.33
+	Hs
		346789 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		MDC1_HUMAN (20-1865): 6.71e-101: 366: 9.14
+	Hs
		346188 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		MAP1B_HUMAN (771-2622): 1.91e-90: 333: 9.59
+	Hs
		346565 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		MUC3A_HUMAN (59-2793): 2.71e-55: 217: 8.31
+	Hs
		379116 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		MAP1B_HUMAN (771-2622): 1.91e-90: 333: 9.59
+	Hs
		347505 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		PRG4_HUMAN (64-1059): 1.94e-35: 151: 8.58
+	Hs
		1056883 MGAP_HUMAN (151-449): 1.22e-27: 118: 17.71		MDC1_HUMAN (20-1865): 6.71e-101: 366: 9.14
+	Hs
		346208 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		PRC2A_HUMAN (513-2601): 5.1e-21: 104: 7.93
+	Hs
		347374 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		BD1L1_HUMAN (98-2862): 2.37e-19: 99.1: 9.63
+	Hs
		348258 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		SRRM2_HUMAN (1748-3241): 1.64e-18: 96: 8.53
+	Hs
		347455 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		TITIN_HUMAN (52-1221): 1.55e-13: 80: 7.85
+	Hs
		347056 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		NIPBL_HUMAN (2321-3191): 7.29e-12: 74.4: 12.83
+	Hs
		379120 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		PRC2A_HUMAN (513-2601): 5.1e-21: 104: 7.93
+	Hs
		380026 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		SRRM2_HUMAN (1748-3241): 1.64e-18: 96: 8.53
+	Hs
		379663 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		TITIN_HUMAN (52-1221): 1.55e-13: 80: 7.85
+	Hs
		1154048 MGAP_HUMAN (151-449): 1.22e-27: 118: 17.71		NIPBL_HUMAN (2321-3191): 7.29e-12: 74.4: 12.83