HitPredict

Interactor 1: MYC (P01106)
Myc proto-oncogene protein (Class E basic helix-loop-helix protein 39) (bHLHe39) (Proto-oncogene c-Myc) (Transcription factor p64)
Gene: MYC

Interactor 2: YBOX1 (P67809)
Y-box-binding protein 1 (YB-1) (CCAAT-binding transcription factor I subunit A) (CBF-A) (DNA-binding protein B) (DBPB) (Enhancer factor I subunit A) (EFI-A) (Nuclease-sensitive element-binding protein 1) (Y-box transcription factor)
Gene: YBX1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.78	0.60	0.686

The method score is based on:

Property	Details
Experiments	29467282, 35013218, 36424410, 21150319
Identification Methods	affinity chromatography technology, proximity labelling technology, tandem affinity purification
Interaction Type	physical association, association

The annotation score is based on:

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0003677 - DNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm and 2 others more... GO:0010468 - regulation of gene expression GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1	454
Hs

1	324

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024