HitPredict

Interactor 1: MYC (P01106)
Myc proto-oncogene protein (Class E basic helix-loop-helix protein 39) (bHLHe39) (Proto-oncogene c-Myc) (Transcription factor p64)
Gene: MYC

Interactor 2: PPIL2 (Q13356)
RING-type E3 ubiquitin-protein ligase PPIL2 (EC 2.3.2.27) (CYC4) (Cyclophilin-60) (Cyclophilin-like protein Cyp-60) (Cyp60) (hCyP-60) (Probable inactive peptidyl-prolyl cis-trans isomerase-like 2) (PPIase) (Rotamase PPIL2)
Gene: PPIL2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	30415952, 36424410
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 454 Hs			1 520
+	Hs
		347871 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		PPIL3_HUMAN (282-438): 2.22e-83: 257: 50.32
+	Hs
		348317 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		PPIL1_HUMAN (270-431): 2.35e-80: 249: 46.91
+	Hs
		345940 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		PPIB_HUMAN (264-443): 7.02e-79: 247: 35.98
+	Hs
		203487 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		PPIH_HUMAN (279-434): 6.67e-77: 241: 38.82
+	Hs
		347109 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		CWC27_HUMAN (280-440): 7.26e-37: 144: 46.91
+	Hs
		380054 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		PPIL1_HUMAN (270-431): 2.35e-80: 249: 46.91
+	Hs
		379021 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		PPIB_HUMAN (264-443): 7.02e-79: 247: 35.98
+	Hs
		203491 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		PPIH_HUMAN (279-434): 6.67e-77: 241: 38.82