HitPredict

Interactor 1: MYC (P01106)
Myc proto-oncogene protein (Class E basic helix-loop-helix protein 39) (bHLHe39) (Proto-oncogene c-Myc) (Transcription factor p64)
Gene: MYC

Interactor 2: FLNC (Q14315)
Filamin-C (FLN-C) (FLNc) (ABP-280-like protein) (ABP-L) (Actin-binding-like protein) (Filamin-2) (Gamma-filamin)
Gene: FLNC

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	29467282, 36424410
Identification Methods	affinity chromatography technology, proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 454 Hs			1 2725
+	Hs
		345916 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		FLNA_HUMAN (167-2725): 0: 1226: 35.27
+	Hs
		347029 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		Q60FE5_HUMAN (167-2725): 0: 1226: 35.27
+	Hs
		261171 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		FLNB_HUMAN (146-2725): 0: 1198: 35.18
+	Hs
		379011 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		FLNA_HUMAN (167-2725): 0: 1226: 35.27
+	Hs
		345805 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		ACTN1_HUMAN (13-382): 6.48e-123: 414: 26.30
+	Hs
		211453 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		ACTN4_HUMAN (16-387): 7.58e-120: 406: 26.68
+	Hs
		346544 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		SPTB2_HUMAN (26-266): 1.26e-100: 365: 38.12
+	Hs
		347372 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		SYNE1_HUMAN (33-344): 6.35e-100: 364: 28.65
+	Hs
		345639 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		FINC_HUMAN (1545-2724): 1.85e-65: 250: 13.83
+	Hs
		378964 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		ACTN1_HUMAN (13-382): 6.48e-123: 414: 26.30
+	Hs
		379631 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		SYNE1_HUMAN (33-344): 6.35e-100: 364: 28.65
+	Hs
		963302 SRBP2_HUMAN (124-446): 8.64e-35: 139: 12.54		SPTB2_HUMAN (26-266): 1.26e-100: 365: 38.12
+	Hs
		347455 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		TITIN_HUMAN (1554-2636): 3.13e-09: 65.5: 10.78
+	Hs
		379663 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		TITIN_HUMAN (1554-2636): 3.13e-09: 65.5: 10.78