HitPredict

Interactor 1: MYC (P01106)
Myc proto-oncogene protein (Class E basic helix-loop-helix protein 39) (bHLHe39) (Proto-oncogene c-Myc) (Transcription factor p64)
Gene: MYC

Interactor 2: DSC3 (Q14574)
Desmocollin-3 (Cadherin family member 3) (Desmocollin-4) (HT-CP)
Gene: DSC3

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	29467282
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 454 Hs			1 896
+	Hs
		346339 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		CAD13_HUMAN (13-682): 0: 598: 33.43
+	Hs
		1218720 MGAP_HUMAN (151-449): 1.22e-27: 118: 17.71		CAD19_HUMAN (120-890): 0: 547: 26.54
+	Hs
		346564 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		DSG1_HUMAN (130-573): 7.15e-68: 247: 32.29
+	Hs
		345887 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		CADH2_HUMAN (2-385): 2.16e-54: 205: 17.55
+	Hs
		60712 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		A5D8W4_HUMAN (278-675): 9.18e-54: 200: 22.46
+	Hs
		346625 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		DSC1_HUMAN (3-347): 3.76e-24: 111: 13.60
+	Hs
		380073 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		PCDB2_HUMAN (2-475): 1.39e-77: 270: 16.36
+	Hs
		346753 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		DSG2_HUMAN (69-391): 3.52e-20: 98.5: 17.85
+	Hs
		379306 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		DSG1_HUMAN (130-573): 7.15e-68: 247: 32.29
+	Hs
		1016120 SRBP2_HUMAN (124-446): 8.64e-35: 139: 12.54		PCDB3_HUMAN (2-475): 2.75e-78: 272: 15.99
+	Hs
		379329 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		DSC1_HUMAN (3-347): 3.76e-24: 111: 13.60
+	Mm
		454965 TFEB_MOUSE (167-450): 3.76e-30: 123: 14.92		CADH1_MOUSE (2-329): 3.81e-26: 117: 16.16