HitPredict

Interactor 1: MYC (P01106)
Myc proto-oncogene protein (Class E basic helix-loop-helix protein 39) (bHLHe39) (Proto-oncogene c-Myc) (Transcription factor p64)
Gene: MYC

Interactor 2: WDR43 (Q15061)
WD repeat-containing protein 43 (U3 small nucleolar RNA-associated protein 5 homolog)
Gene: WDR43

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	30415952, 36424410
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000785 - chromatin GO:0005654 - nucleoplasm GO:0005730 - nucleolus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 454 Hs			1 677
+	Hs
		347517 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		FBXW7_HUMAN (5-295): 1.2e-60: 217: 16.13
+	Mm
		348444 MYC_MOUSE (1-454): 4.33e-119: 357: 89.01		FBXW7_MOUSE (67-390): 1.23e-60: 217: 11.32
+	Hs
		379424 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		WDR43_HUMAN (19-677): 2.5e-119: 372: 100.00
+	Hs
		346404 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		WDR5_HUMAN (157-440): 1.42e-43: 161: 12.11
+	Hs
		346838 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		PWP2_HUMAN (10-270): 1.09e-34: 143: 15.63
+	Hs
		348035 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		NLE1_HUMAN (199-562): 4.61e-28: 120: 9.69
+	Hs
		346310 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		COPA_HUMAN (161-341): 2.58e-24: 111: 10.93
+	Hs
		348241 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		WDR3_HUMAN (9-463): 1.11e-24: 111: 7.53
+	Hs
		267729 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		TAF5L_HUMAN (7-216): 1.61e-21: 101: 19.67
+	Hs
		346159 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		LIS1_HUMAN (204-437): 1.57e-18: 90.3: 9.40
+	Hs
		346933 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		SMU1_HUMAN (117-336): 2.99e-15: 81.1: 18.62
+	Hs
		347550 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		SNR40_HUMAN (251-417): 1.07e-13: 74.8: 4.74
+	Hs
		379688 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		FBXW7_HUMAN (5-295): 1.2e-60: 217: 16.13
+	Mm
		1112323 SRBP2_MOUSE (124-446): 2.23e-37: 147: 13.60		FBXW7_MOUSE (67-390): 1.23e-60: 217: 11.32
+	Hs
		379200 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		WDR5_HUMAN (157-440): 1.42e-43: 161: 12.11
+	Hs
		380022 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		WDR3_HUMAN (9-463): 1.11e-24: 111: 7.53
+	Hs
		607803 USF1_HUMAN (175-453): 1.02e-39: 146: 18.40		WDR5_HUMAN (157-440): 1.42e-43: 161: 12.11
+	Hs
		379460 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		SMU1_HUMAN (117-336): 2.99e-15: 81.1: 18.62
+	Hs
		379701 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		SNR40_HUMAN (251-417): 1.07e-13: 74.8: 4.74
+	Hs
		267736 MYCL_HUMAN (29-449): 4.2e-42: 154: 30.11		TAF5L_HUMAN (7-216): 1.61e-21: 101: 19.67