HitPredict

Interactor 1: MYC (P01106)
Myc proto-oncogene protein (Class E basic helix-loop-helix protein 39) (bHLHe39) (Proto-oncogene c-Myc) (Transcription factor p64)
Gene: MYC

Interactor 2: PRC2B (Q5JSZ5)
Protein PRRC2B (HLA-B-associated transcript 2-like 1) (Proline-rich coiled-coil protein 2B)
Gene: PRRC2B

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	35013218
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 454 Hs			1 2229
+	Hs
		379479 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		PRC2B_HUMAN (1-2229): 0: 619: 100.00
+	Hs
		347056 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		NIPBL_HUMAN (85-1137): 1.88e-36: 154: 11.37
+	Hs
		348258 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		SRRM2_HUMAN (35-1964): 1.44e-35: 151: 8.95
+	Hs
		348352 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		PRC2C_HUMAN (85-2229): 5.01e-29: 130: 8.12
+	Hs
		346758 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		EIF3A_HUMAN (962-1409): 3.68e-26: 120: 14.63
+	Hs
		347455 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		TITIN_HUMAN (65-1179): 1.69e-22: 108: 10.00
+	Hs
		347668 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		MINT_HUMAN (296-2220): 2.45e-17: 91.8: 8.49
+	Hs
		347505 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		PRG4_HUMAN (92-1064): 8.11e-15: 82.9: 8.86
+	Hs
		348379 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		NCOR2_HUMAN (251-2219): 1.19e-14: 82.8: 7.59
+	Hs
		346789 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		MDC1_HUMAN (26-575): 1.86e-13: 78.7: 9.56
+	Hs
		346208 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		PRC2A_HUMAN (971-2229): 8.27e-11: 70.1: 8.24
+	Hs
		346499 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		MAP1A_HUMAN (8-661): 1.5e-10: 69.3: 10.23
+	Hs
		380026 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		SRRM2_HUMAN (35-1964): 1.44e-35: 151: 8.95
+	Hs
		380070 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		PRC2C_HUMAN (85-2229): 5.01e-29: 130: 8.12
+	Hs
		379663 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		TITIN_HUMAN (65-1179): 1.69e-22: 108: 10.00
+	Hs
		1154048 MGAP_HUMAN (151-449): 1.22e-27: 118: 17.71		NIPBL_HUMAN (85-1137): 1.88e-36: 154: 11.37
+	Hs
		379120 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		PRC2A_HUMAN (971-2229): 8.27e-11: 70.1: 8.24
+	Hs
		607835 USF1_HUMAN (175-453): 1.02e-39: 146: 18.40		CIC_HUMAN (42-1044): 8.61e-14: 80.1: 8.37
+	Hs
		1079724 USF2_HUMAN (180-454): 1.78e-35: 136: 15.99		CIC_HUMAN (42-1044): 8.61e-14: 80.1: 8.37
+	Hs
		1056883 MGAP_HUMAN (151-449): 1.22e-27: 118: 17.71		MDC1_HUMAN (26-575): 1.86e-13: 78.7: 9.56