HitPredict

Interactor 1: MYC (P01106)
Myc proto-oncogene protein (Class E basic helix-loop-helix protein 39) (bHLHe39) (Proto-oncogene c-Myc) (Transcription factor p64)
Gene: MYC

Interactor 2: CE170 (Q5SW79)
Centrosomal protein of 170 kDa (Cep170) (KARP-1-binding protein) (KARP1-binding protein)
Gene: CEP170

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.50	0.521

Property	Details
Experiments	35013218, 21150319
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 454 Hs			1 1584
+	Hs
		379487 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		CE170_HUMAN (1-1584): 0: 654: 100.00
+	Hs
		346789 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		MDC1_HUMAN (29-1563): 8.72e-84: 307: 10.03
+	Hs
		346188 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		MAP1B_HUMAN (175-1557): 2.54e-45: 183: 9.56
+	Hs
		346499 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		MAP1A_HUMAN (182-1393): 7.52e-37: 155: 10.27
+	Hs
		347455 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		TITIN_HUMAN (252-1467): 8.36e-24: 112: 8.68
+	Hs
		348258 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		SRRM2_HUMAN (122-1517): 1.29e-18: 95.3: 9.74
+	Hs
		347668 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		MINT_HUMAN (173-1570): 1.59e-17: 91.8: 7.72
+	Hs
		347505 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		PRG4_HUMAN (895-1575): 5.76e-16: 86.3: 11.26
+	Hs
		347056 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		NIPBL_HUMAN (588-1406): 4.52e-15: 83.7: 12.73
+	Hs
		346565 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		MUC3A_HUMAN (115-1573): 1.68e-09: 65.1: 10.42
+	Hs
		1056883 MGAP_HUMAN (151-449): 1.22e-27: 118: 17.71		MDC1_HUMAN (29-1563): 8.72e-84: 307: 10.03
+	Hs
		379116 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		MAP1B_HUMAN (175-1557): 2.54e-45: 183: 9.56
+	Hs
		379663 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		TITIN_HUMAN (252-1467): 8.36e-24: 112: 8.68
+	Hs
		380026 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		SRRM2_HUMAN (122-1517): 1.29e-18: 95.3: 9.74
+	Hs
		297837 K0754_HUMAN (47-360): 3.79e-40: 156: 12.62		C170L_HUMAN (1275-1584): 2.13e-29: 121: 93.23
+	Hs
		1154048 MGAP_HUMAN (151-449): 1.22e-27: 118: 17.71		NIPBL_HUMAN (588-1406): 4.52e-15: 83.7: 12.73