Interactor 1: MYC (P01106)
Myc proto-oncogene protein (Class E basic helix-loop-helix protein 39) (bHLHe39) (Proto-oncogene c-Myc) (Transcription factor p64)
Gene: MYC

Interactor 2: CDC73 (Q6P1J9)
Parafibromin (Cell division cycle protein 73 homolog) (Hyperparathyroidism 2 protein)
Gene: CDC73

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.71 0.60 0.655

The method score is based on:

Property Details
Experiments 26687678, 30415952, 36424410
Identification Methods affinity chromatography technology, unspecified method, proximity labelling technology
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0043066 - negative regulation of apoptotic process
GO:0045944 - positive regulation of transcription by RNA polymerase II
and 1 others

more...

Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 454
Hs

1 531
+ Dm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024