HitPredict

Interactor 1: MYC (P01106)
Myc proto-oncogene protein (Class E basic helix-loop-helix protein 39) (bHLHe39) (Proto-oncogene c-Myc) (Transcription factor p64)
Gene: MYC

Interactor 2: ATAD2 (Q6PL18)
ATPase family AAA domain-containing protein 2 (EC 3.6.1.-) (AAA nuclear coregulator cancer-associated protein) (ANCCA)
Gene: ATAD2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.73	0.60	0.664

Property	Details
Experiments	29467282, 36424410, 19843847
Identification Methods	affinity chromatography technology, proximity labelling technology, pull down
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0045893 - positive regulation of DNA-templated transcription GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 454 Hs			1 1390
+	Hs
		346331 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		TERA_HUMAN (222-748): 9.59e-92: 317: 22.32
+	Hs
		177433 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		NVL_HUMAN (179-707): 1.37e-70: 257: 20.94
+	Hs
		346411 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		PRS4_HUMAN (407-654): 1.22e-48: 182: 42.02
+	Hs
		347346 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		AFG2A_HUMAN (746-1020): 5.64e-29: 127: 13.50
+	Hs
		379205 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		PRS4_HUMAN (407-654): 1.22e-48: 182: 42.02