HitPredict

Interactor 1: MYC (P01106)
Myc proto-oncogene protein (Class E basic helix-loop-helix protein 39) (bHLHe39) (Proto-oncogene c-Myc) (Transcription factor p64)
Gene: MYC

Interactor 2: SRCAP (Q6ZRS2)
Helicase SRCAP (EC 3.6.4.-) (Domino homolog 2) (Snf2-related CBP activator)
Gene: SRCAP

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	29467282, 35140242
Identification Methods	affinity chromatography technology, proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003677 - DNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0006338 - chromatin remodeling GO:0006357 - regulation of transcription by RNA polymerase II and 1 others more... GO:0032991 - protein-containing complex
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 454 Hs			1 3230
+	Hs
		346805 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		CHD4_HUMAN (1959-2633): 3.48e-89: 328: 19.60
+	Hs
		346003 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		SMCA1_HUMAN (2003-2406): 8.09e-92: 327: 26.49
+	Hs
		347406 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		CHD5_HUMAN (1995-2642): 4.91e-88: 324: 19.69
+	Hs
		229271 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		SMCA5_HUMAN (2003-2357): 1.13e-90: 323: 28.77
+	Mm
		348432 MYC_MOUSE (1-454): 4.33e-119: 357: 89.01		CHD4_MOUSE (1959-2647): 3.91e-88: 324: 19.80
+	Hs
		151469 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		CHD2_HUMAN (2039-2386): 6.82e-78: 291: 27.90
+	Hs
		347951 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		CHD8_HUMAN (2021-2361): 3.76e-67: 256: 28.57
+	Hs
		346938 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		CHD9_HUMAN (2026-2350): 4.5e-66: 253: 29.73
+	Hs
		379411 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		CHD4_HUMAN (1959-2633): 3.48e-89: 328: 19.60
+	Hs
		229276 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		SMCA5_HUMAN (2003-2357): 1.13e-90: 323: 28.77
+	Hs
		151473 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		CHD2_HUMAN (2039-2386): 6.82e-78: 291: 27.90
+	Hs
		346268 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		SMCA4_HUMAN (1505-1858): 9.38e-13: 76.9: 13.22
+	Hs
		347609 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		EP400_HUMAN (1085-1716): 1.74e-11: 73: 13.39
+	Hs
		346267 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		SMCA2_HUMAN (1477-1770): 8.82e-09: 63.8: 11.91
+	Mm
		348440 MYC_MOUSE (1-454): 4.33e-119: 357: 89.01		EP400_MOUSE (1024-1716): 9.22e-10: 67.2: 13.77
+	Mm
		348422 MYC_MOUSE (1-454): 4.33e-119: 357: 89.01		SMCA4_MOUSE (1022-1379): 7.86e-09: 64.2: 11.67
+	Hs
		379142 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		SMCA4_HUMAN (1505-1858): 9.38e-13: 76.9: 13.22
+	Hs
		379738 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		EP400_HUMAN (1085-1716): 1.74e-11: 73: 13.39
+	Hs
		379141 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		SMCA2_HUMAN (1477-1770): 8.82e-09: 63.8: 11.91
+	Hs
		519727 MYCL_HUMAN (29-449): 4.2e-42: 154: 30.11		EP400_HUMAN (1085-1716): 1.74e-11: 73: 13.39