HitPredict

Interactor 1: MYC (P01106)
Myc proto-oncogene protein (Class E basic helix-loop-helix protein 39) (bHLHe39) (Proto-oncogene c-Myc) (Transcription factor p64)
Gene: MYC

Interactor 2: H2AV (Q71UI9)
Histone H2A.V (H2A.F/Z) (H2A.Z variant histone 2)
Gene: H2AZ2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	35013218, 36424410
Identification Methods	affinity chromatography technology, proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 454 Hs			1 128
+	Hs
		345764 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		H2AZ_HUMAN (1-127): 3.62e-60: 182: 98.43
+	Hs
		346915 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		H2A2C_HUMAN (5-128): 2.15e-54: 168: 62.40
+	Hs
		347244 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		H2A2B_HUMAN (5-127): 1.29e-54: 168: 60.48
+	Hs
		345670 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		H2A1B_HUMAN (5-125): 1.25e-53: 166: 62.30
+	Hs
		345765 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		H2A1_HUMAN (5-125): 1.18e-53: 166: 62.30
+	Hs
		379535 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		H2AV_HUMAN (1-128): 7.15e-60: 182: 100.00
+	Hs
		379457 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		H2A2C_HUMAN (5-128): 2.15e-54: 168: 62.40
+	Hs
		379580 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		H2A2B_HUMAN (5-127): 1.29e-54: 168: 60.48
+	Hs
		469947 USF1_HUMAN (175-453): 1.02e-39: 146: 18.40		H2AZ_HUMAN (1-127): 3.62e-60: 182: 98.43
+	Hs
		607827 USF1_HUMAN (175-453): 1.02e-39: 146: 18.40		H2AV_HUMAN (1-128): 7.15e-60: 182: 100.00