HitPredict

Interactor 1: MYC (P01106)
Myc proto-oncogene protein (Class E basic helix-loop-helix protein 39) (bHLHe39) (Proto-oncogene c-Myc) (Transcription factor p64)
Gene: MYC

Interactor 2: EMSY (Q7Z589)
BRCA2-interacting transcriptional repressor EMSY
Gene: EMSY

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	30415952, 35140242
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 454 Hs			1 1322
+	Hs
		346565 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		MUC3A_HUMAN (41-1322): 9.65e-39: 161: 10.43
+	Hs
		346789 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		MDC1_HUMAN (94-1250): 3.69e-25: 116: 10.96
+	Hs
		347505 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		PRG4_HUMAN (66-709): 5.07e-17: 89.4: 10.09
+	Hs
		347122 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		SRCAP_HUMAN (588-1312): 6.01e-16: 86: 9.66
+	Hs
		347668 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		MINT_HUMAN (72-1304): 8.31e-15: 82.4: 10.57
+	Hs
		347455 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		TITIN_HUMAN (94-1299): 1.78e-13: 78.2: 9.72
+	Hs
		347033 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		ARID2_HUMAN (125-705): 7.19e-11: 69.4: 16.85
+	Hs
		347189 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		HUWE1_HUMAN (272-823): 7.43e-11: 69.4: 14.11
+	Hs
		379663 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		TITIN_HUMAN (94-1299): 1.78e-13: 78.2: 9.72
+	Hs
		379557 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		HUWE1_HUMAN (272-823): 7.43e-11: 69.4: 14.11
+	Hs
		1056883 MGAP_HUMAN (151-449): 1.22e-27: 118: 17.71		MDC1_HUMAN (94-1250): 3.69e-25: 116: 10.96