HitPredict

Interactor 1: MYC (P01106)
Myc proto-oncogene protein (Class E basic helix-loop-helix protein 39) (bHLHe39) (Proto-oncogene c-Myc) (Transcription factor p64)
Gene: MYC

Interactor 2: PABP2 (Q86U42)
Polyadenylate-binding protein 2 (PABP-2) (Poly(A)-binding protein 2) (Nuclear poly(A)-binding protein 1) (Poly(A)-binding protein II) (PABII) (Polyadenylate-binding nuclear protein 1)
Gene: PABPN1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.68	0.60	0.640

Property	Details
Experiments	29467282, 35013218, 36424410
Identification Methods	affinity chromatography technology, proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000165 - MAPK cascade GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 454 Hs			1 306
+	Hs
		346152 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		RBM34_HUMAN (117-251): 1.51e-30: 121: 31.11
+	Hs
		346288 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		NCBP2_HUMAN (142-298): 5.3e-33: 120: 15.82
+	Hs
		346529 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		RBM3_HUMAN (167-304): 1.15e-32: 119: 22.45
+	Hs
		346749 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		CIRBP_HUMAN (167-306): 3.86e-32: 119: 19.15
+	Hs
		345797 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		PABP1_HUMAN (59-260): 3.2e-22: 98.8: 11.33
+	Hs
		347563 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		DAZP1_HUMAN (163-285): 3.6e-21: 94.6: 21.14
+	Hs
		346697 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		PABP4_HUMAN (163-260): 1.04e-20: 94.2: 17.17
+	Hs
		346042 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		TIA1_HUMAN (167-278): 4.88e-19: 88.4: 15.93
+	Hs
		347396 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		ZCRB1_HUMAN (170-286): 1.58e-16: 78.7: 27.97
+	Hs
		379564 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		PABP2_HUMAN (96-306): 9.35e-43: 150: 100.00
+	Hs
		379099 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		RBM34_HUMAN (117-251): 1.51e-30: 121: 31.11
+	Hs
		379152 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		NCBP2_HUMAN (142-298): 5.3e-33: 120: 15.82
+	Hs
		379295 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		RBM3_HUMAN (167-304): 1.15e-32: 119: 22.45
+	Hs
		379388 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		CIRBP_HUMAN (167-306): 3.86e-32: 119: 19.15
+	Hs
		378957 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		PABP1_HUMAN (59-260): 3.2e-22: 98.8: 11.33
+	Hs
		379709 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		DAZP1_HUMAN (163-285): 3.6e-21: 94.6: 21.14
+	Hs
		379365 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		PABP4_HUMAN (163-260): 1.04e-20: 94.2: 17.17
+	Hs
		379055 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		TIA1_HUMAN (167-278): 4.88e-19: 88.4: 15.93
+	Hs
		379640 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		ZCRB1_HUMAN (170-286): 1.58e-16: 78.7: 27.97