HitPredict

Interactor 1: MYC (P01106)
Myc proto-oncogene protein (Class E basic helix-loop-helix protein 39) (bHLHe39) (Proto-oncogene c-Myc) (Transcription factor p64)
Gene: MYC

Interactor 2: TSYL5 (Q86VY4)
Testis-specific Y-encoded-like protein 5 (TSPY-like protein 5)
Gene: TSPYL5

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	35013218, 36424410
Identification Methods	affinity chromatography technology, proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000785 - chromatin GO:0005634 - nucleus GO:0008284 - positive regulation of cell population proliferation
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 454 Hs			1 417
+	Hs
		379572 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		TSYL5_HUMAN (1-417): 4.15e-164: 469: 100.00
+	Hs
		346548 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		SET_HUMAN (182-384): 7.21e-87: 267: 36.32
+	Hs
		346336 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		NP1L1_HUMAN (158-381): 9.22e-79: 250: 15.53
+	Hs
		379168 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		NP1L1_HUMAN (158-381): 9.22e-79: 250: 15.53
+	Hs
		1314321 MAD3_HUMAN (320-450): 1.2e-25: 105: 26.72		TSYL2_HUMAN (4-400): 5.8e-112: 345: 30.91