HitPredict

Interactor 1: MYC (P01106)
Myc proto-oncogene protein (Class E basic helix-loop-helix protein 39) (bHLHe39) (Proto-oncogene c-Myc) (Transcription factor p64)
Gene: MYC

Interactor 2: CHD1L (Q86WJ1)
Chromodomain-helicase-DNA-binding protein 1-like (EC 3.6.4.-) (Amplified in liver cancer protein 1)
Gene: CHD1L

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	29467282
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0006338 - chromatin remodeling GO:0006974 - DNA damage response
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 454 Hs			1 897
+	Hs
		348113 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		CHD7_HUMAN (2-856): 0: 677: 29.16
+	Hs
		347951 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		CHD8_HUMAN (1-856): 0: 643: 27.69
+	Hs
		346938 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		CHD9_HUMAN (1-856): 0: 636: 28.03
+	Hs
		151469 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		CHD2_HUMAN (11-797): 0: 610: 33.05
+	Hs
		347406 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		CHD5_HUMAN (18-851): 0: 608: 30.09
+	Hs
		229271 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		SMCA5_HUMAN (9-786): 0: 603: 32.60
+	Hs
		346003 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		SMCA1_HUMAN (35-786): 0: 594: 32.63
+	Hs
		346805 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		CHD4_HUMAN (18-775): 0: 584: 32.19
+	Mm
		348432 MYC_MOUSE (1-454): 4.33e-119: 357: 89.01		CHD4_MOUSE (18-775): 0: 584: 32.19
+	Hs
		346268 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		SMCA4_HUMAN (3-782): 0: 567: 29.03
+	Mm
		348422 MYC_MOUSE (1-454): 4.33e-119: 357: 89.01		SMCA4_MOUSE (3-782): 0: 567: 29.80
+	Hs
		346267 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		SMCA2_HUMAN (3-782): 8.8e-177: 555: 28.77
+	Hs
		379973 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		CHD7_HUMAN (2-856): 0: 677: 29.16
+	Hs
		151473 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		CHD2_HUMAN (11-797): 0: 610: 33.05
+	Hs
		229276 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		SMCA5_HUMAN (9-786): 0: 603: 32.60
+	Hs
		379411 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		CHD4_HUMAN (18-775): 0: 584: 32.19
+	Hs
		379142 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		SMCA4_HUMAN (3-782): 0: 567: 29.03
+	Hs
		379141 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		SMCA2_HUMAN (3-782): 8.8e-177: 555: 28.77
+	Hs
		229308 USF1_HUMAN (175-453): 1.02e-39: 146: 18.40		SMCA5_HUMAN (9-786): 0: 603: 32.60
+	Hs
		151368 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		CHD1_HUMAN (40-526): 5.8e-112: 379: 45.51