HitPredict

Interactor 1: MYC (P01106)
Myc proto-oncogene protein (Class E basic helix-loop-helix protein 39) (bHLHe39) (Proto-oncogene c-Myc) (Transcription factor p64)
Gene: MYC

Interactor 2: PHF6 (Q8IWS0)
PHD finger protein 6 (PHD-like zinc finger protein)
Gene: PHF6

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.75	0.60	0.672

Property	Details
Experiments	29467282, 35013218, 36424410, 21150319
Identification Methods	affinity chromatography technology, proximity labelling technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0003677 - DNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005730 - nucleolus
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 454 Hs			1 365
+	Hs
		348225 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		KMT2B_HUMAN (2-364): 8.55e-58: 204: 13.41
+	Hs
		346335 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		BRPF1_HUMAN (9-141): 2.64e-35: 139: 17.24
+	Hs
		346577 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		KMT2A_HUMAN (5-132): 1.13e-27: 116: 24.62
+	Hs
		348155 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		TCF20_HUMAN (32-145): 1.11e-23: 105: 22.81
+	Hs
		379585 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		PHF6_HUMAN (1-365): 7.01e-85: 263: 100.00
+	Hs
		380009 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		BRPF3_HUMAN (4-151): 2.78e-36: 141: 16.25
+	Hs
		379311 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		KMT2A_HUMAN (5-132): 1.13e-27: 116: 24.62
+	Hs
		379985 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		TCF20_HUMAN (32-145): 1.11e-23: 105: 22.81
+	Hs
		379553 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		RAI1_HUMAN (20-132): 3.89e-21: 97.3: 28.32