HitPredict

Interactor 1: MYC (P01106)
Myc proto-oncogene protein (Class E basic helix-loop-helix protein 39) (bHLHe39) (Proto-oncogene c-Myc) (Transcription factor p64)
Gene: MYC

Interactor 2: CCAR1 (Q8IX12)
Cell division cycle and apoptosis regulator protein 1 (Cell cycle and apoptosis regulatory protein 1) (CARP-1) (Death inducer with SAP domain)
Gene: CCAR1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.68	0.60	0.640

Property	Details
Experiments	29467282, 35013218, 36424410
Identification Methods	affinity chromatography technology, proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0008284 - positive regulation of cell population proliferation
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 454 Hs			1 1150
+	Hs
		347303 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		CCAR2_HUMAN (667-1140): 1.1e-32: 139: 27.11
+	Hs
		346089 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		MYH10_HUMAN (407-1150): 2.28e-24: 113: 9.32
+	Hs
		347170 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		MYH14_HUMAN (590-1145): 3.37e-20: 99.7: 14.01
+	Hs
		346088 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		MYH9_HUMAN (710-1150): 5.15e-13: 76.2: 9.03
+	Hs
		346097 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		MYH11_HUMAN (408-887): 2.1e-09: 64.3: 10.33
+	Hs
		379603 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		CCAR2_HUMAN (667-1140): 1.1e-32: 139: 27.11
+	Hs
		379071 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		MYH10_HUMAN (407-1150): 2.28e-24: 113: 9.32
+	Hs
		379550 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		MYH14_HUMAN (590-1145): 3.37e-20: 99.7: 14.01
+	Hs
		379070 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		MYH9_HUMAN (710-1150): 5.15e-13: 76.2: 9.03