HitPredict

Interactor 1: MYC (P01106)
Myc proto-oncogene protein (Class E basic helix-loop-helix protein 39) (bHLHe39) (Proto-oncogene c-Myc) (Transcription factor p64)
Gene: MYC

Interactor 2: MIRO2 (Q8IXI1)
Mitochondrial Rho GTPase 2 (MIRO-2) (hMiro-2) (EC 3.6.5.-) (Ras homolog gene family member T2)
Gene: RHOT2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.50	0.533

Property	Details
Experiments	29467282, 36424410
Identification Methods	affinity chromatography technology, proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 454 Hs			1 618
+	Hs
		346368 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		RAC3_HUMAN (3-168): 9.6e-79: 249: 27.22
+	Hs
		346374 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		CDC42_HUMAN (3-172): 5.67e-77: 244: 25.54
+	Hs
		346522 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		RHOG_HUMAN (3-170): 1.68e-74: 238: 27.47
+	Hs
		346265 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		RAB13_HUMAN (5-180): 1.15e-72: 234: 20.23
+	Hs
		346439 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		RAB1A_HUMAN (416-593): 1.56e-40: 148: 18.28
+	Hs
		347860 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		RAB1B_HUMAN (416-578): 8.51e-39: 143: 19.05
+	Hs
		297812 K0754_HUMAN (47-360): 3.79e-40: 156: 12.62		RAC2_HUMAN (3-183): 1.38e-79: 251: 27.69
+	Hs
		297819 K0754_HUMAN (47-360): 3.79e-40: 156: 12.62		RAC3_HUMAN (3-168): 9.6e-79: 249: 27.22
+	Hs
		297829 K0754_HUMAN (47-360): 3.79e-40: 156: 12.62		RAB35_HUMAN (5-168): 3.51e-76: 242: 24.70
+	Hs
		297827 K0754_HUMAN (47-360): 3.79e-40: 156: 12.62		RHOG_HUMAN (3-170): 1.68e-74: 238: 27.47
+	Hs
		297823 K0754_HUMAN (47-360): 3.79e-40: 156: 12.62		RAC1_HUMAN (3-181): 3.15e-74: 237: 26.43
+	Hs
		894050 USF2_HUMAN (180-454): 1.78e-35: 136: 15.99		CDC42_HUMAN (3-172): 5.67e-77: 244: 25.54
+	Hs
		1016067 SRBP2_HUMAN (124-446): 8.64e-35: 139: 12.54		RB11B_HUMAN (416-572): 8.06e-22: 96.2: 20.37
+	Hs
		297822 K0754_HUMAN (47-360): 3.79e-40: 156: 12.62		RHOB_HUMAN (6-168): 4.57e-13: 70.1: 29.38
+	Hs
		297820 K0754_HUMAN (47-360): 3.79e-40: 156: 12.62		RHOA_HUMAN (6-168): 1.74e-11: 65.5: 28.25
+	Hs
		297841 K0754_HUMAN (47-360): 3.79e-40: 156: 12.62		RHOF_HUMAN (2-167): 3.37e-11: 65.1: 26.67
+	Hs
		297809 K0754_HUMAN (47-360): 3.79e-40: 156: 12.62		RHOC_HUMAN (6-168): 3.86e-11: 64.3: 28.25
+	Hs
		120250 K0754_HUMAN (47-360): 3.79e-40: 156: 12.62		RHOD_HUMAN (3-167): 1.27e-10: 63.2: 28.89