HitPredict

Interactor 1: MYC (P01106)
Myc proto-oncogene protein (Class E basic helix-loop-helix protein 39) (bHLHe39) (Proto-oncogene c-Myc) (Transcription factor p64)
Gene: MYC

Interactor 2: DHX37 (Q8IY37)
Probable ATP-dependent RNA helicase DHX37 (EC 3.6.4.13) (DEAH box protein 37)
Gene: DHX37

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.76	0.60	0.676

Property	Details
Experiments	29467282, 35013218, 36424410, 17353931
Identification Methods	affinity chromatography technology, proximity labelling technology, anti bait coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005730 - nucleolus GO:0005737 - cytoplasm
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 454 Hs			1 1157
+	Hs
		379593 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		DHX37_HUMAN (1-1157): 0: 1100: 100.00
+	Hs
		346620 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		DHX9_HUMAN (9-1017): 0: 790: 21.29
+	Hs
		347175 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		DHX29_HUMAN (8-1010): 0: 738: 21.91
+	Hs
		347873 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		DHX36_HUMAN (126-1020): 0: 719: 22.59
+	Hs
		347072 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		DHX57_HUMAN (136-1009): 0: 708: 23.04
+	Hs
		347150 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		DHX30_HUMAN (181-1007): 0: 626: 24.85
+	Hs
		379326 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		DHX9_HUMAN (9-1017): 0: 790: 21.29
+	Hs
		195304 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		DHX15_HUMAN (442-1029): 0: 616: 23.83
+	Hs
		379855 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		DHX36_HUMAN (126-1020): 0: 719: 22.59
+	Hs
		379510 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		DHX57_HUMAN (136-1009): 0: 708: 23.04
+	Hs
		224742 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		DHX16_HUMAN (552-1029): 1.4e-163: 514: 31.20
+	Hs
		379542 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		DHX30_HUMAN (181-1007): 0: 626: 24.85
+	Hs
		195310 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		DHX15_HUMAN (442-1029): 0: 616: 23.83
+	Hs
		347896 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		DHX33_HUMAN (224-494): 5.09e-47: 182: 41.01