HitPredict

Interactor 1: MYC (P01106)
Myc proto-oncogene protein (Class E basic helix-loop-helix protein 39) (bHLHe39) (Proto-oncogene c-Myc) (Transcription factor p64)
Gene: MYC

Interactor 2: K2C78 (Q8N1N4)
Keratin, type II cytoskeletal 78 (Cytokeratin-78) (CK-78) (Keratin-5b) (Keratin-78) (K78) (Type-II keratin Kb40)
Gene: KRT78

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	35013218
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 454 Hs			1 520
+	Hs
		347191 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		K2C1B_HUMAN (66-435): 6.29e-126: 381: 56.49
+	Hs
		346098 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		K22E_HUMAN (83-427): 1.05e-121: 372: 55.65
+	Hs
		345690 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		K2C8_HUMAN (83-465): 4.86e-121: 365: 55.09
+	Hs
		345661 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		K2C1_HUMAN (76-442): 7.29e-112: 347: 56.95
+	Hs
		347231 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		K2C73_HUMAN (4-513): 9.84e-99: 310: 50.19
+	Hs
		345660 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		K2C6B_HUMAN (76-448): 4.72e-80: 262: 59.25
+	Hs
		345637 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		K2C6A_HUMAN (76-448): 1.02e-78: 258: 59.79
+	Hs
		345816 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		K2C5_HUMAN (76-427): 3.19e-78: 258: 62.50
+	Hs
		379559 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		K2C1B_HUMAN (66-435): 6.29e-126: 381: 56.49
+	Hs
		379075 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		K22E_HUMAN (83-427): 1.05e-121: 372: 55.65
+	Hs
		378892 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		K2C1_HUMAN (76-442): 7.29e-112: 347: 56.95
+	Hs
		379605 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		K2C78_HUMAN (1-520): 1.25e-79: 259: 100.00
+	Hs
		359449 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		K2C6A_HUMAN (76-448): 1.02e-78: 258: 59.79
+	Hs
		378970 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		K2C5_HUMAN (76-427): 3.19e-78: 258: 62.50