HitPredict

Interactor 1: MYC (P01106)
Myc proto-oncogene protein (Class E basic helix-loop-helix protein 39) (bHLHe39) (Proto-oncogene c-Myc) (Transcription factor p64)
Gene: MYC

Interactor 2: UTP15 (Q8TED0)
U3 small nucleolar RNA-associated protein 15 homolog
Gene: UTP15

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.68	0.60	0.640

Property	Details
Experiments	29467282, 36424410, 17353931
Identification Methods	affinity chromatography technology, proximity labelling technology, anti bait coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005730 - nucleolus GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 454 Hs			1 518
+	Hs
		346404 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		WDR5_HUMAN (204-475): 1.14e-54: 188: 13.82
+	Hs
		347517 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		FBXW7_HUMAN (1-188): 1.79e-42: 163: 19.50
+	Hs
		348035 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		NLE1_HUMAN (231-505): 1.44e-43: 162: 10.00
+	Mm
		348444 MYC_MOUSE (1-454): 4.33e-119: 357: 89.01		FBXW7_MOUSE (1-188): 7.44e-43: 164: 19.50
+	Hs
		346638 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		TBL3_HUMAN (91-394): 3.58e-35: 142: 17.34
+	Hs
		347550 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		SNR40_HUMAN (234-447): 2.46e-33: 131: 8.72
+	Hs
		346159 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		LIS1_HUMAN (275-447): 7.1e-21: 96.9: 6.94
+	Hs
		346090 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		COPB2_HUMAN (240-365): 5.92e-12: 70.3: 10.24
+	Hs
		348241 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		WDR3_HUMAN (10-73): 2.76e-10: 64.9: 10.45
+	Hs
		379200 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		WDR5_HUMAN (204-475): 1.14e-54: 188: 13.82
+	Hs
		379688 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		FBXW7_HUMAN (1-188): 1.79e-42: 163: 19.50
+	Hs
		607803 USF1_HUMAN (175-453): 1.02e-39: 146: 18.40		WDR5_HUMAN (204-475): 1.14e-54: 188: 13.82
+	Hs
		379701 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		SNR40_HUMAN (234-447): 2.46e-33: 131: 8.72
+	Mm
		1112323 SRBP2_MOUSE (124-446): 2.23e-37: 147: 13.60		FBXW7_MOUSE (1-188): 7.44e-43: 164: 19.50
+	Hs
		903353 MGAP_HUMAN (151-449): 1.22e-27: 118: 17.71		WDR5_HUMAN (204-475): 1.14e-54: 188: 13.82
+	Mm
		1257396 SRBP1_MOUSE (172-453): 4.45e-35: 140: 16.61		FBXW7_MOUSE (1-188): 7.44e-43: 164: 19.50
+	Hs
		738987 SRBP1_HUMAN (95-453): 2.54e-33: 135: 16.19		FBXW7_HUMAN (1-188): 1.79e-42: 163: 19.50
+	Hs
		380022 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		WDR3_HUMAN (10-73): 2.76e-10: 64.9: 10.45
+	Hs
		1218698 MGAP_HUMAN (151-449): 1.22e-27: 118: 17.71		SNR40_HUMAN (234-447): 2.46e-33: 131: 8.72
+	Hs
		1079733 USF2_HUMAN (180-454): 1.78e-35: 136: 15.99		WDR3_HUMAN (10-73): 2.76e-10: 64.9: 10.45