HitPredict

Interactor 1: MYC (P01106)
Myc proto-oncogene protein (Class E basic helix-loop-helix protein 39) (bHLHe39) (Proto-oncogene c-Myc) (Transcription factor p64)
Gene: MYC

Interactor 2: MY18A (Q92614)
Unconventional myosin-XVIIIa (Molecule associated with JAK3 N-terminus) (MAJN) (Myosin containing a PDZ domain) (Surfactant protein receptor SP-R210) (SP-R210)
Gene: MYO18A

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.571

Property	Details
Experiments	35013218, 21150319
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003677 - DNA binding GO:0005737 - cytoplasm GO:0043066 - negative regulation of apoptotic process
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 454 Hs			1 2054
+	Hs
		346088 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		MYH9_HUMAN (1141-1989): 2.8e-46: 186: 14.96
+	Hs
		347982 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		MYO5C_HUMAN (1119-1615): 4.36e-24: 113: 12.21
+	Hs
		346097 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		MYH11_HUMAN (1684-2053): 3.04e-19: 97.5: 15.00
+	Hs
		346089 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		MYH10_HUMAN (1178-1641): 2.73e-18: 94.4: 14.56
+	Hs
		348342 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		MYO5A_HUMAN (1789-2053): 7.86e-13: 76.7: 12.84
+	Hs
		347170 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		MYH14_HUMAN (1253-1933): 3.46e-11: 71.2: 19.08
+	Hs
		348286 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		MYH15_HUMAN (1248-1834): 8.79e-09: 63.2: 18.86
+	Hs
		379070 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		MYH9_HUMAN (1141-1989): 2.8e-46: 186: 14.96
+	Hs
		379071 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		MYH10_HUMAN (1178-1641): 2.73e-18: 94.4: 14.56
+	Hs
		379550 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		MYH14_HUMAN (1253-1933): 3.46e-11: 71.2: 19.08