HitPredict

Interactor 1: MYC (P01106)
Myc proto-oncogene protein (Class E basic helix-loop-helix protein 39) (bHLHe39) (Proto-oncogene c-Myc) (Transcription factor p64)
Gene: MYC

Interactor 2: SMRD2 (Q92925)
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 2 (60 kDa BRG-1/Brm-associated factor subunit B) (BRG1-associated factor 60B) (BAF60B)
Gene: SMARCD2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	30415952, 35013218
Identification Methods	proximity labelling technology, affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000785 - chromatin GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0006338 - chromatin remodeling GO:0006357 - regulation of transcription by RNA polymerase II and 1 others more... GO:0032991 - protein-containing complex
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 454 Hs			1 531
+	Hs
		347581 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		SMRD1_HUMAN (50-531): 0: 600: 65.11
+	Hs
		347104 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		SMRD3_HUMAN (70-531): 0: 581: 69.70
+	Hs
		379682 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		SMRD2_HUMAN (1-531): 0: 640: 100.00
+	Hs
		379722 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		SMRD1_HUMAN (50-531): 0: 600: 65.11
+	Hs
		738973 SRBP1_HUMAN (95-453): 2.54e-33: 135: 16.19		SMRD3_HUMAN (70-531): 0: 581: 69.70
+	Hs
		297844 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		SC24D_HUMAN (1-148): 2.45e-31: 131: 24.86
+	Hs
		297845 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		SC24D_HUMAN (1-148): 2.45e-31: 131: 24.86