HitPredict

Interactor 1: MYC (P01106)
Myc proto-oncogene protein (Class E basic helix-loop-helix protein 39) (bHLHe39) (Proto-oncogene c-Myc) (Transcription factor p64)
Gene: MYC

Interactor 2: FUBP2 (Q92945)
Far upstream element-binding protein 2 (FUSE-binding protein 2) (KH type-splicing regulatory protein) (KSRP) (p75)
Gene: KHSRP

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.68	0.60	0.640

Property	Details
Experiments	29467282, 35013218, 36424410
Identification Methods	affinity chromatography technology, proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003677 - DNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0010468 - regulation of gene expression
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 454 Hs			1 711
+	Hs
		347530 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		FUBP1_HUMAN (70-707): 2.96e-89: 294: 58.65
+	Hs
		379683 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		FUBP2_HUMAN (1-689): 4.89e-129: 400: 100.00
+	Hs
		379692 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		FUBP1_HUMAN (70-707): 2.96e-89: 294: 58.65
+	Hs
		347594 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		FUBP3_HUMAN (211-701): 4.22e-25: 112: 20.63
+	Hs
		346846 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		PCBP1_HUMAN (52-397): 2.33e-25: 110: 14.25
+	Hs
		127974 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		IF2B3_HUMAN (325-647): 8.75e-23: 105: 15.34
+	Hs
		346847 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		PCBP2_HUMAN (52-400): 2.58e-22: 101: 15.28
+	Hs
		346354 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		PCBP3_HUMAN (19-393): 1.68e-21: 99: 14.36
+	Hs
		346405 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		HNRPK_HUMAN (8-210): 5.64e-11: 67.3: 20.20
+	Hs
		348086 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		IF2B1_HUMAN (61-231): 3.23e-10: 65.5: 16.76
+	Hs
		348394 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		IF2B2_HUMAN (61-211): 4.12e-10: 65.1: 20.26
+	Mm
		348413 MYC_MOUSE (1-454): 4.33e-119: 357: 89.01		HNRPK_MOUSE (8-210): 5.64e-11: 67.3: 20.20
+	Hs
		379728 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		FUBP3_HUMAN (211-701): 4.22e-25: 112: 20.63
+	Hs
		379428 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		PCBP1_HUMAN (52-397): 2.33e-25: 110: 14.25
+	Hs
		127979 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		IF2B3_HUMAN (325-647): 8.75e-23: 105: 15.34
+	Hs
		379429 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		PCBP2_HUMAN (52-400): 2.58e-22: 101: 15.28
+	Hs
		379180 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		PCBP3_HUMAN (19-393): 1.68e-21: 99: 14.36
+	Hs
		379201 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		HNRPK_HUMAN (8-210): 5.64e-11: 67.3: 20.20
+	Hs
		379960 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		IF2B1_HUMAN (61-231): 3.23e-10: 65.5: 16.76
+	Hs
		380081 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		IF2B2_HUMAN (61-211): 4.12e-10: 65.1: 20.26