HitPredict

Interactor 1: MYC (P01106)
Myc proto-oncogene protein (Class E basic helix-loop-helix protein 39) (bHLHe39) (Proto-oncogene c-Myc) (Transcription factor p64)
Gene: MYC

Interactor 2: FBXW7 (Q969H0)
F-box/WD repeat-containing protein 7 (Archipelago homolog) (hAgo) (F-box and WD-40 domain-containing protein 7) (F-box protein FBX30) (SEL-10) (hCdc4)
Gene: FBXW7

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.98 0.60 0.770

The method score is based on:

Property Details
Experiments 22524983, 25720964, 28209614, 28007894, 23750012, 31152129, 31569395, 32021252, 32047362, 31285543, 32345600, 32350066, 33086033, 17646408, 34741373, 35089787, 36002342, 36395886, 36746261, 15498494 and 17 others

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Identification Methods affinity chromatography technology, pull down, enzymatic study, anti bait coimmunoprecipitation, tandem affinity purification, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005730 - nucleolus
GO:0005737 - cytoplasm
GO:0006974 - DNA damage response
and 2 others

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Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 454
Hs

1 707
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024