HitPredict

Interactor 1: MYC (P01106)
Myc proto-oncogene protein (Class E basic helix-loop-helix protein 39) (bHLHe39) (Proto-oncogene c-Myc) (Transcription factor p64)
Gene: MYC

Interactor 2: CHAP1 (Q96JM3)
Chromosome alignment-maintaining phosphoprotein 1 (Zinc finger protein 828)
Gene: CHAMP1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	30415952, 36424410
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 454 Hs			1 812
+	Hs
		379733 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		CHAP1_HUMAN (1-812): 1.59e-115: 371: 100.00
+	Hs
		1218701 MGAP_HUMAN (151-449): 1.22e-27: 118: 17.71		CHAP1_HUMAN (1-812): 1.59e-115: 371: 100.00
+	Hs
		346585 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		IF4G1_HUMAN (112-705): 1.45e-24: 112: 11.69
+	Hs
		347018 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		OBSCN_HUMAN (136-679): 3.63e-21: 102: 15.54
+	Hs
		346789 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		MDC1_HUMAN (135-725): 6.26e-13: 74.9: 9.98
+	Hs
		347489 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		CBP_HUMAN (165-566): 3.23e-11: 69.6: 17.59
+	Hs
		347505 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		PRG4_HUMAN (178-719): 1.85e-10: 66.9: 11.79
+	Hs
		347455 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		TITIN_HUMAN (75-712): 9.93e-10: 64.7: 11.98
+	Hs
		347980 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		SC31B_HUMAN (232-530): 1.05e-09: 64.2: 17.49
+	Hs
		347122 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		SRCAP_HUMAN (140-725): 3.61e-09: 63: 9.53
+	Hs
		379663 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		TITIN_HUMAN (75-712): 9.93e-10: 64.7: 11.98
+	Hs
		1016089 SRBP2_HUMAN (124-446): 8.64e-35: 139: 12.54		CBP_HUMAN (165-566): 3.23e-11: 69.6: 17.59
+	Hs
		738982 SRBP1_HUMAN (95-453): 2.54e-33: 135: 16.19		CBP_HUMAN (165-566): 3.23e-11: 69.6: 17.59
+	Mm
		101440 MITF_MOUSE (155-450): 3.21e-31: 127: 15.11		F8VPR5_MOUSE (205-616): 4.97e-11: 68.9: 18.71
+	Hs
		1056883 MGAP_HUMAN (151-449): 1.22e-27: 118: 17.71		MDC1_HUMAN (135-725): 6.26e-13: 74.9: 9.98
+	Hs
		1218680 MGAP_HUMAN (151-449): 1.22e-27: 118: 17.71		CRBG2_HUMAN (169-686): 9.38e-11: 68.1: 17.08