HitPredict

Interactor 1: MYC (P01106)
Myc proto-oncogene protein (Class E basic helix-loop-helix protein 39) (bHLHe39) (Proto-oncogene c-Myc) (Transcription factor p64)
Gene: MYC

Interactor 2: WDR18 (Q9BV38)
WD repeat-containing protein 18
Gene: WDR18

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	36424410
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005730 - nucleolus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 454 Hs			1 432
+	Hs
		347517 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		FBXW7_HUMAN (66-406): 4.11e-66: 225: 18.26
+	Mm
		348444 MYC_MOUSE (1-454): 4.33e-119: 357: 89.01		FBXW7_MOUSE (10-292): 4.47e-69: 233: 18.47
+	Hs
		347550 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		SNR40_HUMAN (113-413): 1.61e-57: 194: 14.80
+	Hs
		346404 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		WDR5_HUMAN (152-432): 8.2e-55: 186: 14.75
+	Hs
		348035 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		NLE1_HUMAN (1-106): 3.14e-28: 117: 19.63
+	Hs
		346159 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		LIS1_HUMAN (247-430): 5.11e-28: 116: 14.29
+	Hs
		346645 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		CDC20_HUMAN (31-153): 3.74e-13: 72.9: 15.52
+	Hs
		379688 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		FBXW7_HUMAN (66-406): 4.11e-66: 225: 18.26
+	Hs
		379701 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		SNR40_HUMAN (113-413): 1.61e-57: 194: 14.80
+	Hs
		379200 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		WDR5_HUMAN (152-432): 8.2e-55: 186: 14.75
+	Mm
		1112323 SRBP2_MOUSE (124-446): 2.23e-37: 147: 13.60		FBXW7_MOUSE (10-292): 4.47e-69: 233: 18.47
+	Mm
		1257396 SRBP1_MOUSE (172-453): 4.45e-35: 140: 16.61		FBXW7_MOUSE (10-292): 4.47e-69: 233: 18.47
+	Hs
		738987 SRBP1_HUMAN (95-453): 2.54e-33: 135: 16.19		FBXW7_HUMAN (66-406): 4.11e-66: 225: 18.26
+	Dm
		1375911 MYC_DROME (210-454): 3.25e-30: 126: 26.74		FBXW7_DROME (5-292): 1.99e-58: 209: 17.41
+	Hs
		607803 USF1_HUMAN (175-453): 1.02e-39: 146: 18.40		WDR5_HUMAN (152-432): 8.2e-55: 186: 14.75
+	Hs
		1218698 MGAP_HUMAN (151-449): 1.22e-27: 118: 17.71		SNR40_HUMAN (113-413): 1.61e-57: 194: 14.80
+	Hs
		903353 MGAP_HUMAN (151-449): 1.22e-27: 118: 17.71		WDR5_HUMAN (152-432): 8.2e-55: 186: 14.75
+	Mm
		659344 MAX_MOUSE (354-454): 3.52e-25: 102: 32.67		WDR5_MOUSE (152-432): 8.2e-55: 186: 14.75
+	Hs
		898091 MAX_HUMAN (354-454): 1.39e-24: 101: 32.67		WDR5_HUMAN (152-432): 8.2e-55: 186: 14.75
+	Hs
		840206 MXI1_HUMAN (321-450): 2.55e-29: 116: 27.69		CDC20_HUMAN (31-153): 3.74e-13: 72.9: 15.52