HitPredict

Interactor 1: MYC (P01106)
Myc proto-oncogene protein (Class E basic helix-loop-helix protein 39) (bHLHe39) (Proto-oncogene c-Myc) (Transcription factor p64)
Gene: MYC

Interactor 2: MK67I (Q9BYG3)
MKI67 FHA domain-interacting nucleolar phosphoprotein (Nucleolar phosphoprotein Nopp34) (Nucleolar protein interacting with the FHA domain of pKI-67) (hNIFK)
Gene: NIFK

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.68	0.60	0.640

Property	Details
Experiments	29467282, 35013218, 36424410
Identification Methods	affinity chromatography technology, proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005730 - nucleolus GO:0005737 - cytoplasm
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 454 Hs			1 293
+	Hs
		346545 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		TIAR_HUMAN (39-289): 7.08e-48: 165: 13.44
+	Hs
		346042 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		TIA1_HUMAN (40-289): 7.87e-47: 163: 12.89
+	Hs
		346697 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		PABP4_HUMAN (35-225): 7.16e-41: 151: 14.66
+	Hs
		345797 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		PABP1_HUMAN (35-225): 1.96e-40: 150: 14.14
+	Hs
		348168 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		PUF60_HUMAN (31-234): 4.14e-30: 120: 17.96
+	Hs
		346655 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		ELAV2_HUMAN (38-128): 7.23e-24: 101: 26.37
+	Hs
		346857 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		SF3B4_HUMAN (26-283): 2.83e-17: 83.3: 11.92
+	Hs
		345974 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		ELAV4_HUMAN (144-223): 1.03e-10: 63.6: 8.54
+	Hs
		379829 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		MK67I_HUMAN (1-293): 8.07e-53: 176: 100.00
+	Hs
		379302 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		TIAR_HUMAN (39-289): 7.08e-48: 165: 13.44
+	Hs
		379055 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		TIA1_HUMAN (40-289): 7.87e-47: 163: 12.89
+	Hs
		379365 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		PABP4_HUMAN (35-225): 7.16e-41: 151: 14.66
+	Hs
		378957 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		PABP1_HUMAN (35-225): 1.96e-40: 150: 14.14
+	Hs
		379994 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		PUF60_HUMAN (31-234): 4.14e-30: 120: 17.96
+	Hs
		380046 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		RBMX2_HUMAN (14-235): 3.77e-30: 117: 17.54
+	Hs
		379345 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		ELAV2_HUMAN (38-128): 7.23e-24: 101: 26.37
+	Hs
		379406 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		ELAV3_HUMAN (14-127): 3.93e-23: 99.1: 16.00
+	Hs
		379435 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		SF3B4_HUMAN (26-283): 2.83e-17: 83.3: 11.92
+	Hs
		379036 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		ELAV4_HUMAN (144-223): 1.03e-10: 63.6: 8.54