HitPredict

Interactor 1: MYC (P01106)
Myc proto-oncogene protein (Class E basic helix-loop-helix protein 39) (bHLHe39) (Proto-oncogene c-Myc) (Transcription factor p64)
Gene: MYC

Interactor 2: DDX24 (Q9GZR7)
ATP-dependent RNA helicase DDX24 (EC 3.6.4.13) (DEAD box protein 24)
Gene: DDX24

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.86	0.60	0.722

Property	Details
Experiments	17353931, 29467282, 30415952, 35013218, 36424410, 21150319
Identification Methods	affinity chromatography technology, proximity labelling technology, anti bait coimmunoprecipitation, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005730 - nucleolus
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 454 Hs			1 859
+	Hs
		348398 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		DDX49_HUMAN (335-829): 3.53e-136: 416: 26.79
+	Hs
		133814 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		DDX3X_HUMAN (158-723): 2.85e-123: 388: 19.08
+	Hs
		345867 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		DDX5_HUMAN (232-774): 1.14e-121: 382: 19.89
+	Hs
		379842 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		DDX24_HUMAN (1-859): 8.65e-159: 487: 100.00
+	Hs
		133830 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		DDX3X_HUMAN (158-723): 2.85e-123: 388: 19.08
+	Hs
		379911 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		DDX4_HUMAN (44-719): 5.74e-122: 387: 17.83
+	Hs
		378997 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		DDX5_HUMAN (232-774): 1.14e-121: 382: 19.89
+	Hs
		348030 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		DDX18_HUMAN (391-740): 1.22e-32: 137: 29.69
+	Hs
		348185 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		DDX41_HUMAN (390-691): 7.07e-32: 134: 31.17
+	Hs
		347225 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		DDX42_HUMAN (4-267): 1.44e-16: 86.7: 14.61
+	Hs
		347859 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		DDX47_HUMAN (177-261): 2.92e-12: 71.7: 36.47
+	Hs
		347494 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		DDX17_HUMAN (130-267): 9.12e-12: 70.9: 21.43
+	Hs
		379930 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		DDX18_HUMAN (391-740): 1.22e-32: 137: 29.69
+	Hs
		379997 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		DDX41_HUMAN (390-691): 7.07e-32: 134: 31.17
+	Hs
		379851 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		DDX47_HUMAN (177-261): 2.92e-12: 71.7: 36.47
+	Hs
		379679 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		DDX17_HUMAN (130-267): 9.12e-12: 70.9: 21.43
+	Zm
		6054 A0A1D6K972_MAIZE (112-445): 1.88e-29: 123: 15.10		A0A1D6E625_MAIZE (114-261): 1.15e-27: 122: 25.00