HitPredict

Interactor 1: MYC (P01106)
Myc proto-oncogene protein (Class E basic helix-loop-helix protein 39) (bHLHe39) (Proto-oncogene c-Myc) (Transcription factor p64)
Gene: MYC

Interactor 2: UN45A (Q9H3U1)
Protein unc-45 homolog A (Unc-45A) (GCUNC-45) (Smooth muscle cell-associated protein 1) (SMAP-1)
Gene: UNC45A

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.68	0.60	0.640

Property	Details
Experiments	29467282, 35013218, 17353931
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 454 Hs			1 944
+	Hs
		898194 MAX_HUMAN (354-454): 1.39e-24: 101: 32.67		UN45A_HUMAN (1-944): 0: 1027: 100.00
+	Hs
		347899 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		RPAP3_HUMAN (15-343): 5.32e-41: 163: 17.06
+	Hs
		348233 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		CHIP_HUMAN (8-159): 1.54e-35: 139: 29.30
+	Hs
		174528 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		OGT1_HUMAN (3-192): 2.53e-24: 112: 12.63
+	Hs
		346052 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		STIP1_HUMAN (4-228): 9.18e-17: 86.8: 15.32
+	Hs
		348154 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		Z3H7B_HUMAN (21-143): 1.06e-11: 71.2: 33.33
+	Mm
		291319 MYCB_MOUSE (16-189): 8.18e-37: 134: 58.05		TTC3_MOUSE (7-436): 3.44e-44: 176: 13.17
+	Hs
		1016098 SRBP2_HUMAN (124-446): 8.64e-35: 139: 12.54		TTC1_HUMAN (11-172): 2.98e-40: 152: 28.49
+	Dm
		1366986 MYC_DROME (210-454): 3.25e-30: 126: 26.74		Q9VH81_DROME (6-180): 1.39e-38: 153: 22.29
+	Hs
		379984 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		Z3H7B_HUMAN (21-143): 1.06e-11: 71.2: 33.33
+	Hs
		252936 MITF_HUMAN (155-450): 1.47e-29: 123: 14.47		CHIP_HUMAN (8-159): 1.54e-35: 139: 29.30
+	Hs
		585131 TFEB_HUMAN (180-450): 2.56e-28: 118: 14.59		CHIP_HUMAN (8-159): 1.54e-35: 139: 29.30
+	Dm
		1366985 Q9W4Q7_DROME (358-449): 5.64e-19: 91.7: 29.03		Q9VH81_DROME (6-180): 1.39e-38: 153: 22.29
+	Mm
		1208456 MLXPL_MOUSE (70-447): 2.06e-31: 129: 14.14		OGT1_MOUSE (3-192): 2.11e-24: 112: 12.63