HitPredict

Interactor 1: MYC (P01106)
Myc proto-oncogene protein (Class E basic helix-loop-helix protein 39) (bHLHe39) (Proto-oncogene c-Myc) (Transcription factor p64)
Gene: MYC

Interactor 2: XPO5 (Q9HAV4)
Exportin-5 (Exp5) (Ran-binding protein 21)
Gene: XPO5

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.71	0.60	0.656

Property	Details
Experiments	36424410, 17314511, 17353931
Identification Methods	proximity labelling technology, affinity chromatography technology, anti bait coimmunoprecipitation, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 454 Hs			1 1204
+	Hs
		162323 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		XPO1_HUMAN (3-923): 0: 589: 15.25
+	Hs
		348361 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		TNPO3_HUMAN (3-854): 4.28e-136: 439: 13.56
+	Hs
		162327 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		XPO1_HUMAN (3-923): 0: 589: 15.25
+	Hs
		163302 MLXIP_HUMAN (9-446): 1.64e-52: 191: 13.83		XPO1_HUMAN (3-923): 0: 589: 15.25
+	Hs
		207869 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		XPOT_HUMAN (21-846): 2.2e-106: 360: 13.84
+	Hs
		162255 MITF_HUMAN (155-450): 1.47e-29: 123: 14.47		XPO1_HUMAN (3-923): 0: 589: 15.25
+	Hs
		162396 TFEB_HUMAN (180-450): 2.56e-28: 118: 14.59		XPO1_HUMAN (3-923): 0: 589: 15.25
+	Hs
		162570 MAX_HUMAN (354-454): 1.39e-24: 101: 32.67		XPO1_HUMAN (3-923): 0: 589: 15.25
+	Hs
		297143 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		IPO13_HUMAN (7-987): 8.16e-86: 302: 13.28
+	Hs
		346330 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		XPO2_HUMAN (3-925): 1.33e-75: 272: 11.84
+	Hs
		348174 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		XPO7_HUMAN (4-560): 3.48e-15: 83: 13.04