HitPredict

Interactor 1: MYC (P01106)
Myc proto-oncogene protein (Class E basic helix-loop-helix protein 39) (bHLHe39) (Proto-oncogene c-Myc) (Transcription factor p64)
Gene: MYC

Interactor 2: PDS5B (Q9NTI5)
Sister chromatid cohesion protein PDS5 homolog B (Androgen-induced proliferation inhibitor) (Androgen-induced prostate proliferative shutoff-associated protein AS3)
Gene: PDS5B

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.66	0.60	0.633

Property	Details
Experiments	29467282, 17353931, 21150319
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000785 - chromatin GO:0003677 - DNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 454 Hs			1 1447
+	Hs
		346926 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		PDS5A_HUMAN (2-1362): 0: 1442: 66.94
+	Hs
		379919 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		PDS5B_HUMAN (1-1424): 0: 1569: 100.00
+	Hs
		1100527 MGAP_HUMAN (151-449): 1.22e-27: 118: 17.71		PDS5A_HUMAN (2-1362): 0: 1442: 66.94
+	Hs
		347186 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		RBBP6_HUMAN (949-1444): 2.32e-29: 130: 13.58
+	Hs
		347126 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		CRACD_HUMAN (1006-1446): 2.39e-23: 109: 9.23
+	Hs
		347056 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		NIPBL_HUMAN (1008-1443): 5.96e-17: 89.6: 11.11
+	Hs
		347603 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		CHAP1_HUMAN (1177-1442): 4.55e-10: 66.5: 10.53
+	Hs
		347505 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		PRG4_HUMAN (1045-1440): 1.21e-09: 65.3: 11.09
+	Hs
		347455 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		TITIN_HUMAN (1006-1366): 6.67e-09: 63.4: 9.86
+	Hs
		379555 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		RBBP6_HUMAN (949-1444): 2.32e-29: 130: 13.58
+	Hs
		379733 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		CHAP1_HUMAN (1177-1442): 4.55e-10: 66.5: 10.53
+	Hs
		379663 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		TITIN_HUMAN (1006-1366): 6.67e-09: 63.4: 9.86
+	Hs
		1154048 MGAP_HUMAN (151-449): 1.22e-27: 118: 17.71		NIPBL_HUMAN (1008-1443): 5.96e-17: 89.6: 11.11
+	Hs
		1218701 MGAP_HUMAN (151-449): 1.22e-27: 118: 17.71		CHAP1_HUMAN (1177-1442): 4.55e-10: 66.5: 10.53