HitPredict

Interactor 1: MYC (P01106)
Myc proto-oncogene protein (Class E basic helix-loop-helix protein 39) (bHLHe39) (Proto-oncogene c-Myc) (Transcription factor p64)
Gene: MYC

Interactor 2: PLAP (Q9Y263)
Phospholipase A-2-activating protein (PLA2P) (PLAP)
Gene: PLAA

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	29467282
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 454 Hs			1 795
+	Hs
		347517 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		FBXW7_HUMAN (142-456): 2.86e-61: 221: 19.00
+	Mm
		348444 MYC_MOUSE (1-454): 4.33e-119: 357: 89.01		FBXW7_MOUSE (142-456): 6.82e-62: 223: 19.00
+	Hs
		348277 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		FBW1A_HUMAN (138-358): 8.68e-41: 160: 18.03
+	Hs
		348035 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		NLE1_HUMAN (5-138): 2.15e-29: 124: 18.52
+	Hs
		346449 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		GBB2_HUMAN (167-416): 5.33e-30: 123: 12.31
+	Hs
		347932 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		GBB4_HUMAN (182-416): 3.56e-29: 121: 13.17
+	Hs
		346404 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		WDR5_HUMAN (324-622): 4.79e-28: 117: 12.33
+	Hs
		346090 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		COPB2_HUMAN (316-579): 2.4e-17: 88.9: 7.90
+	Hs
		346159 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		LIS1_HUMAN (373-532): 3.92e-11: 67.8: 10.00
+	Hs
		267729 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		TAF5L_HUMAN (34-178): 6.87e-10: 64.3: 30.67
+	Hs
		379688 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		FBXW7_HUMAN (142-456): 2.86e-61: 221: 19.00
+	Mm
		1112323 SRBP2_MOUSE (124-446): 2.23e-37: 147: 13.60		FBXW7_MOUSE (142-456): 6.82e-62: 223: 19.00
+	Mm
		1257396 SRBP1_MOUSE (172-453): 4.45e-35: 140: 16.61		FBXW7_MOUSE (142-456): 6.82e-62: 223: 19.00
+	Hs
		738987 SRBP1_HUMAN (95-453): 2.54e-33: 135: 16.19		FBXW7_HUMAN (142-456): 2.86e-61: 221: 19.00
+	Hs
		379200 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		WDR5_HUMAN (324-622): 4.79e-28: 117: 12.33
+	Hs
		252937 MITF_HUMAN (155-450): 1.47e-29: 123: 14.47		FBW1A_HUMAN (138-358): 8.68e-41: 160: 18.03
+	Hs
		252935 MITF_HUMAN (155-450): 1.47e-29: 123: 14.47		FBW1B_HUMAN (3-179): 1.11e-34: 141: 22.34
+	Hs
		607803 USF1_HUMAN (175-453): 1.02e-39: 146: 18.40		WDR5_HUMAN (324-622): 4.79e-28: 117: 12.33
+	Hs
		267736 MYCL_HUMAN (29-449): 4.2e-42: 154: 30.11		TAF5L_HUMAN (34-178): 6.87e-10: 64.3: 30.67
+	Dm
		1375911 MYC_DROME (210-454): 3.25e-30: 126: 26.74		FBXW7_DROME (14-297): 4.13e-16: 85.1: 27.21