HitPredict

Interactor 1: MYC (P01106)
Myc proto-oncogene protein (Class E basic helix-loop-helix protein 39) (bHLHe39) (Proto-oncogene c-Myc) (Transcription factor p64)
Gene: MYC

Interactor 2: AMOL2 (Q9Y2J4)
Angiomotin-like protein 2 (Leman coiled-coil protein) (LCCP)
Gene: AMOTL2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.50	0.521

Property	Details
Experiments	35013218, 21150319
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 454 Hs			1 779
+	Hs
		346952 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		AMOT_HUMAN (1-740): 2.7e-70: 252: 32.32
+	Hs
		346088 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		MYH9_HUMAN (16-773): 4.81e-28: 123: 9.57
+	Hs
		346097 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		MYH11_HUMAN (207-773): 7.92e-24: 110: 11.36
+	Hs
		346089 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		MYH10_HUMAN (222-773): 1.7e-23: 109: 10.95
+	Hs
		347019 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		MRCKA_HUMAN (242-732): 6.78e-18: 91.3: 12.33
+	Hs
		348121 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		CING_HUMAN (175-776): 2.05e-17: 89.3: 9.97
+	Hs
		380035 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		AMOL2_HUMAN (1-779): 1.36e-71: 251: 100.00
+	Hs
		347982 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		MYO5C_HUMAN (85-502): 3.91e-13: 75.5: 11.37
+	Hs
		345843 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		DESP_HUMAN (16-454): 7.49e-11: 68.1: 12.02
+	Hs
		346834 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		PLEC_HUMAN (191-769): 1.21e-09: 64.3: 9.88
+	Hs
		348261 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		SMC3_HUMAN (220-710): 6.48e-09: 61.6: 14.34
+	Hs
		379070 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		MYH9_HUMAN (16-773): 4.81e-28: 123: 9.57
+	Hs
		379071 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		MYH10_HUMAN (222-773): 1.7e-23: 109: 10.95
+	Hs
		378986 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		DESP_HUMAN (16-454): 7.49e-11: 68.1: 12.02
+	Hs
		1218737 MGAP_HUMAN (151-449): 1.22e-27: 118: 17.71		SMC3_HUMAN (220-710): 6.48e-09: 61.6: 14.34
+	Hs
		840228 MXI1_HUMAN (321-450): 2.55e-29: 116: 27.69		SMC3_HUMAN (220-710): 6.48e-09: 61.6: 14.34
+	Hs
		983450 MAD1_HUMAN (320-453): 2.08e-29: 116: 19.40		SMC3_HUMAN (220-710): 6.48e-09: 61.6: 14.34
+	Hs
		1055889 MAD4_HUMAN (320-449): 5.66e-28: 112: 23.85		SMC3_HUMAN (220-710): 6.48e-09: 61.6: 14.34
+	Hs
		1314327 MAD3_HUMAN (320-450): 1.2e-25: 105: 26.72		SMC3_HUMAN (220-710): 6.48e-09: 61.6: 14.34