HitPredict

Interactor 1: MYC (P01106)
Myc proto-oncogene protein (Class E basic helix-loop-helix protein 39) (bHLHe39) (Proto-oncogene c-Myc) (Transcription factor p64)
Gene: MYC

Interactor 2: ZN281 (Q9Y2X9)
Zinc finger protein 281 (GC-box-binding zinc finger protein 1) (Transcription factor ZBP-99) (Zinc finger DNA-binding protein 99)
Gene: ZNF281

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.75 0.60 0.672

The method score is based on:

Property Details
Experiments 29467282, 30415952, 17314511
Identification Methods affinity chromatography technology, proximity labelling technology, two hybrid, tandem affinity purification
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001227 - DNA-binding transcription repressor activity, RNA polymerase II-specific
GO:0005634 - nucleus
and 2 others

more...
Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 454
Hs

1 895
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024