HitPredict

Interactor 1: MYC (P01108)
Myc proto-oncogene protein (Proto-oncogene c-Myc) (Transcription factor p64)
Gene: MYC

Interactor 2: MAX (P28574)
Protein max (Myc-associated factor X) (Myc-binding novel HLH/LZ protein) (Protein myn)
Gene: MAX

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.73 1.00 0.858

The method score is based on:

Property Details
Experiments 1840505, 20211142, 20946988, 20434984
Identification Methods genetic interference, two hybrid array, pull down, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation
Interaction Type association, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains HLH~HLH, HLH~Myc-LZ
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0003677 - DNA binding
GO:0003700 - DNA-binding transcription factor activity
GO:0005634 - nucleus
and 10 others

more...
Homologous interactions 17

Homologous interactions

Color coding for hit scores

1 454
Mm

1 160
+ Rn
+ Hs
+ Hs
+ Mm
+ Hs
+ Hs
+ Hs
+ Gg
+ Mm
+ Hs
+ Hs
+ At
+ At
+ At
+ Mm
+ At
+ At

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024