HitPredict - High confidence protein-protein interactions

Interactor 1: MYC (P01108)
Myc proto-oncogene protein (Proto-oncogene c-Myc) (Transcription factor p64)
Gene: MYC

Interactor 2: HIF1A (Q61221)
Hypoxia-inducible factor 1-alpha (HIF-1-alpha) (HIF1-alpha) (ARNT-interacting protein)
Gene: HIF1A

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Interacting Pfam domains	HLH~PAS
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0000791 - euchromatin GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific GO:0003677 - DNA binding and 15 others more... GO:0003700 - DNA-binding transcription factor activity GO:0005634 - nucleus GO:0006355 - regulation of DNA-templated transcription GO:0006357 - regulation of transcription by RNA polymerase II GO:0006879 - intracellular iron ion homeostasis GO:0008284 - positive regulation of cell population proliferation GO:0010468 - regulation of gene expression GO:0010629 - negative regulation of gene expression GO:0031625 - ubiquitin protein ligase binding GO:0043565 - sequence-specific DNA binding GO:0044877 - protein-containing complex binding GO:0045893 - positive regulation of DNA-templated transcription GO:0045944 - positive regulation of transcription by RNA polymerase II GO:0048661 - positive regulation of smooth muscle cell proliferation GO:0070888 - E-box binding
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1	454
Mm

1	836

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024