HitPredict

Interactor 1: MYC (P01108)
Myc proto-oncogene protein (Proto-oncogene c-Myc) (Transcription factor p64)
Gene: MYC

Interactor 2: DDX20 (Q9JJY4)
Probable ATP-dependent RNA helicase DDX20 (EC 3.6.1.15) (EC 3.6.4.13) (Component of gems 3) (DEAD box protein 20) (DEAD box protein DP 103) (Gemin-3) (Regulator of steroidogenic factor 1) (ROSF-1)
Gene: DDX20

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	23665319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0003677 - DNA binding GO:0090571 - RNA polymerase II transcription repressor complex
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 454 Mm			1 825
+	Hs
		348165 MYC_HUMAN (1-454): 2.17e-123: 368: 89.23		DDX20_HUMAN (3-825): 0: 680: 82.52
+	Hs
		345969 MYC_HUMAN (1-454): 2.17e-123: 368: 89.23		DDX6_HUMAN (12-446): 3.27e-151: 453: 31.19
+	Hs
		347494 MYC_HUMAN (1-454): 2.17e-123: 368: 89.23		DDX17_HUMAN (3-462): 4.46e-128: 402: 24.41
+	Hs
		345867 MYC_HUMAN (1-454): 2.17e-123: 368: 89.23		DDX5_HUMAN (1-475): 5.92e-129: 400: 22.79
+	Hs
		347225 MYC_HUMAN (1-454): 2.17e-123: 368: 89.23		DDX42_HUMAN (13-761): 3.16e-122: 392: 18.89
+	Hs
		347404 MYC_HUMAN (1-454): 2.17e-123: 368: 89.23		DDX54_HUMAN (5-757): 4.12e-121: 388: 17.71
+	Hs
		346115 MYC_HUMAN (1-454): 2.17e-123: 368: 89.23		IF4A3_HUMAN (34-445): 3.73e-122: 375: 32.20
+	Hs
		379032 MYCN_HUMAN (12-451): 1.36e-67: 225: 33.33		DDX6_HUMAN (12-446): 3.27e-151: 453: 31.19
+	Hs
		379679 MYCN_HUMAN (12-451): 1.36e-67: 225: 33.33		DDX17_HUMAN (3-462): 4.46e-128: 402: 24.41
+	Hs
		378997 MYCN_HUMAN (12-451): 1.36e-67: 225: 33.33		DDX5_HUMAN (1-475): 5.92e-129: 400: 22.79
+	Hs
		379643 MYCN_HUMAN (12-451): 1.36e-67: 225: 33.33		DDX54_HUMAN (5-757): 4.12e-121: 388: 17.71
+	Hs
		346738 MYC_HUMAN (1-454): 2.17e-123: 368: 89.23		DX39B_HUMAN (55-441): 1.86e-67: 232: 35.13
+	Hs
		379085 MYCN_HUMAN (12-451): 1.36e-67: 225: 33.33		IF4A3_HUMAN (34-445): 3.73e-122: 375: 32.20
+	Hs
		117076 MYC_HUMAN (1-454): 2.17e-123: 368: 89.23		DX39A_HUMAN (55-441): 1.73e-66: 229: 34.10
+	Mm
		1144894 TFE3_MOUSE (182-450): 4.64e-27: 115: 15.75		Q8BTS0_MOUSE (1-475): 2.63e-129: 401: 22.79
+	Mm
		1144918 TFE3_MOUSE (182-450): 4.64e-27: 115: 15.75		IF4A3_MOUSE (34-445): 8.32e-122: 375: 32.20
+	Hs
		379384 MYCN_HUMAN (12-451): 1.36e-67: 225: 33.33		DX39B_HUMAN (55-441): 1.86e-67: 232: 35.13
+	Hs
		117078 MYCN_HUMAN (12-451): 1.36e-67: 225: 33.33		DX39A_HUMAN (55-441): 1.73e-66: 229: 34.10
+	Hs
		738966 SRBP1_HUMAN (96-453): 2.56e-41: 159: 15.70		DX39B_HUMAN (55-441): 1.86e-67: 232: 35.13