HitPredict

Interactor 1: RASN (P01111)
GTPase NRas (EC 3.6.5.2) (Transforming protein N-Ras)
Gene: NRAS

Interactor 2: LYN (P07948)
Tyrosine-protein kinase Lyn (EC 2.7.10.2) (Lck/Yes-related novel protein tyrosine kinase) (V-yes-1 Yamaguchi sarcoma viral related oncogene homolog) (p53Lyn) (p56Lyn)
Gene: LYN

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.68	0.60	0.640

Property	Details
Experiments	30442766, 30639242, 30194290
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005794 - Golgi apparatus GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0070062 - extracellular exosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 189 Hs			1 512
+	Hs
		349807 RASK_HUMAN (16-189): 7.56e-85: 249: 85.71		LYN_HUMAN (1-512): 0: 611: 100.00
+	Hs
		433769 RAB35_HUMAN (4-171): 6.96e-84: 247: 34.71		LYN_HUMAN (1-512): 0: 611: 100.00
+	Hs
		349070 RASH_HUMAN (1-188): 8.6e-78: 232: 85.64		LYN_HUMAN (1-512): 0: 611: 100.00
+	Hs
		349836 RASK_HUMAN (16-189): 7.56e-85: 249: 85.71		SRC_HUMAN (1-510): 0: 580: 51.97
+	Hs
		349806 RASK_HUMAN (16-189): 7.56e-85: 249: 85.71		YES_HUMAN (1-510): 0: 572: 54.26
+	Hs
		433358 RAB35_HUMAN (4-171): 6.96e-84: 247: 34.71		YES_HUMAN (1-510): 0: 572: 54.26
+	Hs
		348488 RASN_HUMAN (1-189): 9.9e-80: 236: 100.00		SRC_HUMAN (1-510): 0: 580: 51.97
+	Hs
		349095 RASH_HUMAN (1-188): 8.6e-78: 232: 85.64		SRC_HUMAN (1-510): 0: 580: 51.97
+	Rn
		589762 RASH_RAT (1-188): 8.6e-78: 232: 85.64		SRC_RAT (1-510): 0: 577: 51.97
+	Hs
		348473 RASN_HUMAN (1-189): 9.9e-80: 236: 100.00		YES_HUMAN (1-510): 0: 572: 54.26
+	Hs
		349066 RASH_HUMAN (1-188): 8.6e-78: 232: 85.64		FYN_HUMAN (1-510): 0: 576: 54.12
+	Hs
		349069 RASH_HUMAN (1-188): 8.6e-78: 232: 85.64		YES_HUMAN (1-510): 0: 572: 54.26
+	Hs
		522882 RB11A_HUMAN (4-184): 1.5e-74: 224: 33.88		SRC_HUMAN (1-510): 0: 580: 51.97
+	Hs
		433312 RB11A_HUMAN (4-184): 1.5e-74: 224: 33.88		YES_HUMAN (1-510): 0: 572: 54.26
+	Hs
		433306 RAB2A_HUMAN (4-185): 1.53e-73: 222: 31.52		YES_HUMAN (1-510): 0: 572: 54.26
+	Hs
		349949 RASK_HUMAN (16-189): 7.56e-85: 249: 85.71		ABL2_HUMAN (14-509): 1.38e-171: 517: 36.61
+	Hs
		349172 RASH_HUMAN (1-188): 8.6e-78: 232: 85.64		ABL2_HUMAN (14-509): 1.38e-171: 517: 36.61
+	Hs
		350101 RASK_HUMAN (16-189): 7.56e-85: 249: 85.71		BTK_HUMAN (2-505): 1.48e-156: 462: 33.86
+	Hs
		348630 RASN_HUMAN (1-189): 9.9e-80: 236: 100.00		BTK_HUMAN (2-505): 1.48e-156: 462: 33.86
+	Hs
		349264 RASH_HUMAN (1-188): 8.6e-78: 232: 85.64		BTK_HUMAN (2-505): 1.48e-156: 462: 33.86