HitPredict

Interactor 1: RASN (P01111)
GTPase NRas (EC 3.6.5.2) (Transforming protein N-Ras)
Gene: NRAS

Interactor 2: PTN1 (P18031)
Tyrosine-protein phosphatase non-receptor type 1 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1B) (PTP-1B)
Gene: PTPN1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	30194290
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 189 Hs			1 435
+	Hs
		349861 RASK_HUMAN (16-189): 7.56e-85: 249: 85.71		PTN1_HUMAN (1-435): 0: 539: 100.00
+	Hs
		573703 RAB35_HUMAN (4-171): 6.96e-84: 247: 34.71		PTN1_HUMAN (1-435): 0: 539: 100.00
+	Hs
		573653 RB11A_HUMAN (4-184): 1.5e-74: 224: 33.88		PTN1_HUMAN (1-435): 0: 539: 100.00
+	Hs
		350120 RASK_HUMAN (16-189): 7.56e-85: 249: 85.71		PTPRJ_HUMAN (2-301): 3.29e-123: 389: 33.44
+	Hs
		349275 RASH_HUMAN (1-188): 8.6e-78: 232: 85.64		PTPRJ_HUMAN (2-301): 3.29e-123: 389: 33.44
+	Hs
		914038 RB11A_HUMAN (4-184): 1.5e-74: 224: 33.88		PTPRJ_HUMAN (2-301): 3.29e-123: 389: 33.44
+	Hs
		1031987 RAB35_HUMAN (4-171): 6.96e-84: 247: 34.71		PTPRS_HUMAN (1-278): 3.66e-109: 355: 30.74
+	Hs
		349822 RASK_HUMAN (16-189): 7.56e-85: 249: 85.71		PTPRF_HUMAN (19-278): 2.99e-105: 344: 30.94
+	Hs
		489965 RAB35_HUMAN (4-171): 6.96e-84: 247: 34.71		PTPRF_HUMAN (19-278): 2.99e-105: 344: 30.94
+	Hs
		349083 RASH_HUMAN (1-188): 8.6e-78: 232: 85.64		PTPRF_HUMAN (19-278): 2.99e-105: 344: 30.94
+	Hs
		489934 RAB2A_HUMAN (4-185): 1.53e-73: 222: 31.52		PTPRF_HUMAN (19-278): 2.99e-105: 344: 30.94
+	Hs
		349111 RASH_HUMAN (1-188): 8.6e-78: 232: 85.64		PTPRA_HUMAN (12-278): 9.1e-105: 330: 31.62
+	Hs
		349902 RASK_HUMAN (16-189): 7.56e-85: 249: 85.71		PTPRM_HUMAN (7-281): 2.32e-63: 223: 26.48
+	Hs
		349143 RASH_HUMAN (1-188): 8.6e-78: 232: 85.64		PTPRM_HUMAN (7-281): 2.32e-63: 223: 26.48
+	Hs
		349136 RASH_HUMAN (1-188): 8.6e-78: 232: 85.64		PTN3_HUMAN (3-275): 1.72e-49: 182: 36.43
+	Hs
		914025 RB11A_HUMAN (4-184): 1.5e-74: 224: 33.88		PTN11_HUMAN (39-274): 7.78e-49: 177: 38.80
+	Hs
		349881 RASK_HUMAN (16-189): 7.56e-85: 249: 85.71		PTPRG_HUMAN (342-435): 1.43e-21: 99.7: 13.46
+	Hs
		617112 RAB35_HUMAN (4-171): 6.96e-84: 247: 34.71		PTPRG_HUMAN (342-435): 1.43e-21: 99.7: 13.46
+	Hs
		348514 RASN_HUMAN (1-189): 9.9e-80: 236: 100.00		PTPRG_HUMAN (342-435): 1.43e-21: 99.7: 13.46
+	Hs
		617093 RAB2A_HUMAN (4-185): 1.53e-73: 222: 31.52		PTPRG_HUMAN (342-435): 1.43e-21: 99.7: 13.46