HitPredict

Interactor 1: RASN (P01111)
GTPase NRas (EC 3.6.5.2) (Transforming protein N-Ras)
Gene: NRAS

Interactor 2: AT2B4 (P23634)
Plasma membrane calcium-transporting ATPase 4 (PMCA4) (EC 7.2.2.10) (Matrix-remodeling-associated protein 1) (Plasma membrane calcium ATPase isoform 4) (Plasma membrane calcium pump isoform 4)
Gene: ATP2B4

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	30442766, 30194290
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0016020 - membrane
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 189 Hs			1 1241
+	Hs
		349882 RASK_HUMAN (16-189): 7.56e-85: 249: 85.71		AT2B4_HUMAN (1-1241): 0: 1300: 100.00
+	Hs
		619234 RAB35_HUMAN (4-171): 6.96e-84: 247: 34.71		AT2B4_HUMAN (1-1241): 0: 1300: 100.00
+	Hs
		349129 RASH_HUMAN (1-188): 8.6e-78: 232: 85.64		AT2B4_HUMAN (1-1241): 0: 1300: 100.00
+	Hs
		349870 RASK_HUMAN (16-189): 7.56e-85: 249: 85.71		AT2B1_HUMAN (1-1241): 0: 1148: 72.46
+	Hs
		588605 RAB35_HUMAN (4-171): 6.96e-84: 247: 34.71		AT2B1_HUMAN (1-1241): 0: 1148: 72.46
+	Hs
		348504 RASN_HUMAN (1-189): 9.9e-80: 236: 100.00		AT2B1_HUMAN (1-1241): 0: 1148: 72.46
+	Hs
		349116 RASH_HUMAN (1-188): 8.6e-78: 232: 85.64		AT2B1_HUMAN (1-1241): 0: 1148: 72.46
+	Hs
		588580 RB11A_HUMAN (4-184): 1.5e-74: 224: 33.88		AT2B1_HUMAN (1-1241): 0: 1148: 72.46
+	Hs
		588573 RAB2A_HUMAN (4-185): 1.53e-73: 222: 31.52		AT2B1_HUMAN (1-1241): 0: 1148: 72.46
+	Hs
		349796 RASK_HUMAN (16-189): 7.56e-85: 249: 85.71		AT1A1_HUMAN (34-1053): 0: 737: 23.37
+	Hs
		393215 RAB35_HUMAN (4-171): 6.96e-84: 247: 34.71		AT1A1_HUMAN (34-1053): 0: 737: 23.37
+	Hs
		348468 RASN_HUMAN (1-189): 9.9e-80: 236: 100.00		AT1A1_HUMAN (34-1053): 0: 737: 23.37
+	Hs
		349060 RASH_HUMAN (1-188): 8.6e-78: 232: 85.64		AT1A1_HUMAN (34-1053): 0: 737: 23.37
+	Hs
		393146 RB11A_HUMAN (4-184): 1.5e-74: 224: 33.88		AT1A1_HUMAN (34-1053): 0: 737: 23.37
+	Hs
		393132 RAB2A_HUMAN (4-185): 1.53e-73: 222: 31.52		AT1A1_HUMAN (34-1053): 0: 737: 23.37