HitPredict

Interactor 1: RASN (P01111)
GTPase NRas (EC 3.6.5.2) (Transforming protein N-Ras)
Gene: NRAS

Interactor 2: ADDB (P35612)
Beta-adducin (Erythrocyte adducin subunit beta)
Gene: ADD2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	30442766, 30639242
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0005886 - plasma membrane
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 189 Hs			1 726
+	Hs
		350647 RASK_HUMAN (16-189): 7.56e-85: 249: 85.71		ADDG_HUMAN (1-726): 0: 793: 53.28
+	Hs
		1070437 RAB35_HUMAN (4-171): 6.96e-84: 247: 34.71		ADDG_HUMAN (1-726): 0: 793: 53.28
+	Hs
		348983 RASN_HUMAN (1-189): 9.9e-80: 236: 100.00		ADDG_HUMAN (1-726): 0: 793: 53.28
+	Hs
		349700 RASH_HUMAN (1-188): 8.6e-78: 232: 85.64		ADDG_HUMAN (1-726): 0: 793: 53.28
+	Hs
		349930 RASK_HUMAN (16-189): 7.56e-85: 249: 85.71		ADDB_HUMAN (1-715): 0: 774: 100.00
+	Hs
		726035 RAB35_HUMAN (4-171): 6.96e-84: 247: 34.71		ADDB_HUMAN (1-715): 0: 774: 100.00
+	Hs
		914430 RB11A_HUMAN (4-184): 1.5e-74: 224: 33.88		ADDG_HUMAN (1-726): 0: 793: 53.28
+	Hs
		895307 RAB2A_HUMAN (4-185): 1.53e-73: 222: 31.52		ADDG_HUMAN (1-726): 0: 793: 53.28
+	Hs
		349159 RASH_HUMAN (1-188): 8.6e-78: 232: 85.64		ADDB_HUMAN (1-715): 0: 774: 100.00
+	Hs
		349929 RASK_HUMAN (16-189): 7.56e-85: 249: 85.71		ADDA_HUMAN (1-715): 0: 733: 46.07
+	Hs
		725956 RAB35_HUMAN (4-171): 6.96e-84: 247: 34.71		ADDA_HUMAN (1-715): 0: 733: 46.07
+	Hs
		348543 RASN_HUMAN (1-189): 9.9e-80: 236: 100.00		ADDA_HUMAN (1-715): 0: 733: 46.07
+	Hs
		349158 RASH_HUMAN (1-188): 8.6e-78: 232: 85.64		ADDA_HUMAN (1-715): 0: 733: 46.07
+	Hs
		725935 RAB2A_HUMAN (4-185): 1.53e-73: 222: 31.52		ADDA_HUMAN (1-715): 0: 733: 46.07
+	Hs
		297806 RASK_HUMAN (16-189): 7.56e-85: 249: 85.71		K0754_HUMAN (348-726): 1.73e-22: 105: 12.30
+	Hs
		297829 RAB35_HUMAN (4-171): 6.96e-84: 247: 34.71		K0754_HUMAN (348-726): 1.73e-22: 105: 12.30
+	Hs
		297805 RASN_HUMAN (1-189): 9.9e-80: 236: 100.00		K0754_HUMAN (348-726): 1.73e-22: 105: 12.30
+	Hs
		350405 RASK_HUMAN (16-189): 7.56e-85: 249: 85.71		TITIN_HUMAN (390-723): 2.53e-09: 63.1: 10.87
+	Hs
		914253 RB11A_HUMAN (4-184): 1.5e-74: 224: 33.88		TITIN_HUMAN (390-723): 2.53e-09: 63.1: 10.87