HitPredict

Interactor 1: RASN (P01111)
GTPase NRas (EC 3.6.5.2) (Transforming protein N-Ras)
Gene: NRAS

Interactor 2: MTOR (P42345)
Serine/threonine-protein kinase mTOR (EC 2.7.11.1) (FK506-binding protein 12-rapamycin complex-associated protein 1) (FKBP12-rapamycin complex-associated protein) (Mammalian target of rapamycin) (mTOR) (Mechanistic target of rapamycin) (Rapamycin and FKBP12 target 1) (Rapamycin target protein 1)
Gene: MTOR

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.65 1.00 0.812

The method score is based on:

Property Details
Experiments 30639242, 34591642
Identification Methods proximity labelling technology, affinity chromatography technology, far western blotting, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains PI3_PI4_kinase~Ras
Common GO terms GO:0000139 - Golgi membrane
GO:0005789 - endoplasmic reticulum membrane
GO:0005829 - cytosol
GO:0016020 - membrane
Homologous interactions 15

Homologous interactions

Color coding for hit scores

1 189
Hs

1 2549
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024