Interactor 1: AIFM1 (O95831)
Apoptosis-inducing factor 1, mitochondrial (EC 1.6.99.-) (Programmed cell death protein 8)
Gene: AIFM1

Interactor 2: MIA40 (Q8N4Q1)
Mitochondrial intermembrane space import and assembly protein 40 (Coiled-coil-helix-coiled-coil-helix domain-containing protein 4)
Gene: CHCHD4

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.83 0.55 0.676

The method score is based on:

Property Details
Experiments 33961781, 29568061, 34079125, unassigned1655, unassigned3799
Identification Methods affinity chromatography technology, proximity labelling technology, pull down, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005739 - mitochondrion
GO:0005758 - mitochondrial intermembrane space
GO:0033108 - mitochondrial respiratory chain complex assembly
GO:0045041 - protein import into mitochondrial intermembrane space
GO:0160203 - mitochondrial disulfide relay system
Homologous interactions 0

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Last updated: 11Aug2025